To study the outcome in boys with a history of UTI or with persistent incontinence who underwent cystoscopy and endoscopic treatment in case of obstruction, compared to boys who did not have cystoscopy.
ID
Source
Brief title
Condition
- Urethral disorders (excl calculi)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Micturition frequency, voided volume, LUTS, incontinence episodes, episodes of
UTI.
Secondary outcome
Obstipation, additional treatments: training, medication, surgery.
Background summary
Infravesical obstruction in boys may be the cause of urinary tract infection
(UTI), lower urinary tract symptoms (LUTS) or incontinence. It is unsure
whether cystoscopy with concomitant treatment of obstruction, should be part of
the diagnostic protocol in boys after a first UTI within the first year of life
(group 1) or in case of persisting urinary incontinence (UI) in boys (group 2).
Study objective
To study the outcome in boys with a history of UTI or with persistent
incontinence who underwent cystoscopy and endoscopic treatment in case of
obstruction, compared to boys who did not have cystoscopy.
Study design
This is an observational cohort study
Study burden and risks
Two questionnaires and a micturition diary (24 hours).
Heidelberglaan 100
3584 CX
Nederland
Heidelberglaan 100
3584 CX
Nederland
Listed location countries
Age
Inclusion criteria
Group 1:
- Male sex
- Proven UTI (urinary tract infection)
- Age <12 months of age at time of UTI
- Presenting with UTI between January 2004 and December 2007 in the Wilhelmina Children*s Hospital Utrecht OR presenting with UTI between 2002 and 2005 in the Emma Children*s Hospital Amsterdam
- Willing and able to participate in the study
- Signed informed consent;Group 2:
- Male sex
- age < 18 years
- UI despite1 year of conservative treatment
- Cystoscopy in the Wilhelmina Children*s Hospital Utrecht between January 2007 and December 2009 AND suspicion of infravesical obstruction OR tertiary referral for incontinence to the Erasmus Medical Center Rotterdam between 2006 and 2009
- Willing and able to participate in the study
- Signed informed consent
Exclusion criteria
Neurogenic bladder disorder or suspicion of neurogenic bladder disorder
(Suspicion of) UPJ-stenosis
Previous cystoscopy
Cystoscopy in combination with other treatment of the upper urinary tract (e.g. deflux injections, pyeloplasty, ureteral reimplantation)
Mental retardation
Syndromal disorder
Hypospadias
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL36457.041.11 |