Purpose:We like to determine the movement of the intestinal contents to measure the peristaltic movement/ motility.
ID
Source
Brief title
Condition
- Malignant and unspecified neoplasms gastrointestinal NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
- migration of the radio-opaque markers
Secondary outcome
time till first faeces production in stoma or rectal after surgery
Background summary
Introduction:
After colorectal surgery anastomotic leakage is one of the most important
complications. This complication has high impact on morbidity and mortality
rate. [1,2] Several studies show that a temporary diverting ileostomy protect
the distal anastomosis, especially when anastomosis is nearby the rectum.
One of the arguments for a diverting stomy is to prevent faecal contamination
of the anatomosis. However, programmes for enhanced recovery after colorectal
surgery abolished mechanical bowel preparation. As a consequence faeces remains
in the descending loop that can pass the anastomosis. Interestingly, the
incidence rate of anastomotic leakage has not been increased after installation
of ERAS- programmes. This is shown both in the Amphia Hospital as in other
hospitals. [3,4]
It suggests another cause for the protective role of the ileostomy than
preventing fecal contamination. We suggest an alternative possibility, that the
stomy prevents continuation of the peristaltic wave along the gut and in this
way reduces the intracolonic pressure on the anastomosis.
Study objective
Purpose:
We like to determine the movement of the intestinal contents to measure the
peristaltic movement/ motility.
Study design
Observational study
Study burden and risks
The risk and extend of burden for the patient is minimal. Radiation pollution
will be in total two x-rays of the abdomen, this will be in total 0.3 mSievert
per x-ray.
The colonic transit time will be determined with one capsule which contain
twelve radiopaque rings, so-called Sitzmarker. This capsule dissolves very easy
in the gastro-intestinal tract. When the capsule dissolves, the twelve rings
will pursue their way through the colon or remain in position in cases without
no or less motility.
Molengracht 21
4818 CK Breda
NL
Molengracht 21
4818 CK Breda
NL
Listed location countries
Age
Inclusion criteria
elective:
low anterior resection with ileostomy
right hemicolectomie
ileostomy closure
Exclusion criteria
immunocompromised
weak pre- operative condition
neo adjuvant chemo radiationtherapy
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL34570.008.11 |