Comparison of preoperative diets before bariatric surgery: a randomized controlled trial

Morbid obesity, defined as a body mass index (BMI) of > 40 kg/m² or > 35 kg/m²
with obesity-related comorbidities, is a rapidly growing problem in the western
society. In the United States, about 6 million people currently have a BMI of >
40 kg/m² and another 10 million people have a BMI of > 35 kg/m² with
comorbidities. Worldwide, the incidence of morbid obesity has doubled and about
300 million people are now obese [1, 2]. In the Netherlands the prevalence is
less disturbing but the incidence of morbid obesity is rising progressively to
1.5% of the total population [3]. At this moment surgical therapy is the only
treatment option for these patients that results in sufficient long-term weight
loss. Non-surgical approaches, like low energy diets and behavior modification,
are not successful in the long-term with respect to maintaining weight loss and
decreasing obesity-related comorbidities[4, 5].
In order to increase weight loss and minimize complications a preoperative diet
before bariatric has been advocated. However, the usual VLCD's are poorly
tolerated by patients. In this study we aim to compare two preoperative diets
in order to find the most suitable for this patient population.

Comparison of preoperative diets before bariatric surgery with a randomized
non-inferiority trial in order to compare the standard VLCD with a standard
diet.

Randomized clinical trial of two preoperative diets before bariatric surgery
(gastric bypass) comparing standard diet and Prodimed

Preoperative diet

No risks.
Burden: 1 questionnaire, 1 diet book filled out during 10 days and 1 extra OPD
visit.
Total: 120 minutes