to describe neurophysiological characteristics of *writhing* and *fidgety* GMs in typically developing young infants by means of multiple surface EMG recordings and kinematics.
ID
Source
Brief title
Condition
- Congenital and peripartum neurological conditions
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
General Movements: parameters of complexity and variation in muscle activity
and kinematics
Secondary outcome
General Movements (GMs): phasic burst duration and amplitude, degree of
antagonistic co-contraction
Background summary
Around 180.000 infants are born in the Netherlands every year (CBS). Most of
them are healthy and will develop typically, but some children will develop a
motor disorder. It is important to determine as early as possible which infants
are at risk for developmental motor disorders in order to be able to provide
optimal treatment and guidance for those infants and their parents.
The assessment of general movements (GMs) is a non-invasive clinical tool
trying to identify infants at risk for developmental disorders. In clinical
practise the quality of general movements is based on video-recordings. It is
important to investigate the neurological characteristics of typically
developing infants more precisely in order to get a better understanding of
typical and atypical neuromotor behaviour.
Study objective
to describe neurophysiological characteristics of *writhing* and *fidgety* GMs
in typically developing young infants by means of multiple surface EMG
recordings and kinematics.
Study design
small descriptive cohort study
Study burden and risks
The infants will be assessed twice (at 1 and 3 months of age). The assessments
will take place at home. Surface EMG electrodes and small markers will be
attached to the skin of the infant. Previous studies indicated that infants
tolerate these small devices well. If the child gets tired, crying or hungry,
the assesment is stopped and, if possible, continued at a later point in time.
There are no risks associated with participation. Parents will fill out a short
questionnaire on prenatal, perinatal and neonatal history (10 minutes). The
benefit of the study in general consists of novel information on
neurophysiology underlying parts of the infant neurological examination. This
information can only be obtained by studying infants. Benefits of participation
for infant and family consist of getting detailed information on the child*s
current developmental status.
Hanzeplein 1
Groningen 9713 GZ
NL
Hanzeplein 1
Groningen 9713 GZ
NL
Listed location countries
Age
Inclusion criteria
Healthy full-term infant, i.e. an infant born after a gestational age of at least 37 weeks without prenatal, perinatal or neonatal complications, younger than 1 month of age (first assessment at age of 1 month)
Exclusion criteria
Admission to the paediatric department of a hospital;
Severe congenital abnormalities, such as serious congenital heart disorders or a chromosomal condition;
Birthweight below the tenth percentile;
Neurological abnormalities;
Parents have insufficient understanding of the Dutch language
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL41373.042.12 |