To develop an MR scanning protocol for pancreatic cancer
ID
Source
Brief title
Condition
- Gastrointestinal neoplasms malignant and unspecified
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
An MRI scanning protocol suitable for diagnosis and surgical and radiotherapy
treatment planning for the treatment of pancreatic carcinoma.
Secondary outcome
N/A
Background summary
The current gold standard in evaluation of suspected pancreatic cancer is CT.
Unfortunately, this technique has poor soft tissue discrimination. In practice
the presence of a tumour is often suspected, but the tumor cannot be
visualized. MRI can be expected to be able to visualize the tumor, due to
better soft-tissue contrast. Still, international literature lacks a sufficient
scanning protocol. This needs to be developed. The development of this MRI
protocol will be used by the department of surgery, gastroenterology and
radiology for diagnostic purposes and to determine resectability. Also, this
MRI protocol can be used to finally develop a non-invasive radiotherapy
treatment, using an MRI linear accelerator which is developed in our hospital.
Study objective
To develop an MR scanning protocol for pancreatic cancer
Study design
Observational study
Study burden and risks
Patients will undergo one contrast enhanced MRI scan with a maximal duration of
45 minutes. For determination of renal function, one peripheral venipuncture is
needed if no recent value (<3 months) is reported in the patient*s medical
chart. After proper screening, the use of MRI is free of any risks. The use of
Gadovist has a very low risk of contrast enhanced allergy. For the patients
included in the study there is no individual benefit.
Heidelberglaan 100
Utrecht 3584 CX
NL
Heidelberglaan 100
Utrecht 3584 CX
NL
Listed location countries
Age
Inclusion criteria
- Patients suspected of having pancreatic cancer
- >18 years
- No previous pancreatic surgery, pancreatic radiotherapy or chemotherapy
- Written informed consent
Exclusion criteria
- Creatinin clearance of <60mL/min/1.73m2
- Known Gadovist allergy
- Patients who meet exclusion criteria for MRI following the protocol of the radiology
department of the UMC Utrecht
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL39754.041.12 |