Research with human participants

Overview of medical research in the Netherlands

The Validation of PFA-200 in the measurement of platelet activation

Published:
Last updated:

To validate the initial flow rate and total volume

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Ethical review
Approved WMO
Status
Recruitment stopped
Health condition type
Other condition
Study type
Observational invasive

ID

NL-OMON37505

Source

ToetsingOnline

Brief title

PFA-200

Condition

  • Other condition

Synonym

Healthy volunteers

Health condition

Geen aandoeningen

Research involving

Human

Sponsors and support

Primary sponsor :
Vrije Universiteit Medisch Centrum
Source(s) of monetary or material Support :
VUmc 51072

Intervention

Keyword :
PFA-200, Platelet

Outcome measures

Primary outcome

Initial flow rate and tortal volume

Secondary outcome

N.a.

Background summary

The PFA-200 is a new device which we hope to use to measure the level of
platelet activation.
We use the initial flow rate and total volume, these parameters have not yet
been validated.

Study objective

To validate the initial flow rate and total volume

Study design

We take blood from the subjects and measure initial flow rate and total volume
using the PFA-200

Study burden and risks

Minimal

Public
Vrije Universiteit Medisch Centrum

De Boelelaan 1117 1117
Amsterdam 1081 HV
NL
Scientific
Vrije Universiteit Medisch Centrum

De Boelelaan 1117 1117
Amsterdam 1081 HV
NL

Listed location countries

Netherlands

Age

Adults (18-64 years)
Elderly (65 years and older)

Inclusion criteria

Age: 18-30
Healthy volunteers

Exclusion criteria

Aspirine use
Other recent medication use which will infuence platelet activation (e.g. NSAID's, SSRI's)
Cardiovascular disease

Design

Study type :
Observational invasive
Masking :
Open (masking not used)
Control :
Uncontrolled
Primary purpose :
Diagnostic

Recruitment

NL
Recruitment status
:
Recruitment stopped
Start date (anticipated) :
Enrollment :
30
Type :
Actual

Approved WMO
Date :
Application type :
First submission
Review commission :
METC Amsterdam UMC

Followed up by the following (possibly more current) registration

No registrations found.

Other (possibly less up-to-date) registrations in this register

No registrations found.

In other registers

Register ID
CCMO NL40220.029.12