Primary Objective : What is the correlation between the CO and the delay in time between injecting the contrast medium and arrival of the contrast in the abdominal aorta Secondary Objective : Would it be possible to reduce the amount of contrast…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Alle patienten die komen voor CT abdomen.
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
- The cardiac output, measured by the Nexfin Monitor.
- The time delay, starting when the contrast medium is injected until the time
that de necessary amount of Hounsfield Units is reached.
Secondary outcome
- The correlation coefficient between the cardiac output and the delay time.
Background summary
In this investigation will be observed whether the testbolus technique can be
replaced by a cardiac output measurement. This might be possible, if the
correlation between the cardiac output and the delay can be described.
Both investigations are meant to reduce the total amount of contrast medium
that's being used. This is a very important goal, as the use of contrast media
could cause CIN (contrast induced nephropathy). Another advantage in the
future will be that the low dose scans in testbolus/bolustriggering technique
won't be necessary anymore for dertermination of delay time. This saves a small
amount of radiation.
Study objective
Primary Objective : What is the correlation between the CO and the delay in
time between injecting the contrast medium and arrival of the contrast in the
abdominal aorta
Secondary Objective : Would it be possible to reduce the amount of contrast
medium used in CT of the abdomen by using CO measurements as a replacement for
test bolus technique?
Study design
This is a correlation study.
Study burden and risks
The patient will be subjected to a small amount of radiation, approximately 0,4
mSV, because of the low dose scans that will be made for measuring time delay.
The additional amount of radiation is relatively small compared to the whole
scan. The radiation on the whole scan is 10 mSv, depending on the size of the
scan area. This is the amount of radiation that the patient always will
receive for medical indication.
Henri Dunantstraat 1
5223 GZ 's-Hertogenbosch
NL
Henri Dunantstraat 1
5223 GZ 's-Hertogenbosch
NL
Listed location countries
Age
Inclusion criteria
Referred for CTA of the abdominal aorta according to clinical indications
Mentally competent
Signed informed consent
* 18 years
Kidney function * 60 GFR
Exclusion criteria
< 18 years
Mentally incompetent
Kidney function < 60 GFR
Allergy contrast medium
Known arrhythmias or other heart disorders
Pregnancy or lactation
16,9 * BMI * 30,1
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL39634.028.12 |