The main purpose of the current study is to evaluate whether patients with CMP have a higher energy expenditure during walking a prescribed distance or climbing a prescribed number of stair steps than healthy volunteers.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
a-specifieke musculoskeletale pijnklachten aan het bewegingsapparaat (chronische lage rugpijn en fibromyalgie)
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study parameter is the difference in energy expenditure per task
during walking and stair climbing between subjects with CMP and healthy
volunteers.
Secondary outcome
Differences in energy expenditure per minute during walking and stair climbing
between subjects with CMP and healthy volunteers.
Differences in energy expenditure per minute during walking and stair climbing
between subjects with CLBP and FM.
Differences in time needed to complete both tests between subjects with CMP and
healthy volunteers.
Energy expenditure per performed task measured with the Sense Wear Pro Armband
Background summary
Chronic musculoskeletal pain (CMP) is an important public health problem due to
high impact on disability, quality of life, and health care costs. CMP has an
unknown cause and pathology and affects the everyday life of many people. It is
characterized by widespread pain, fatigue, and cognitive symptoms. The
fear-avoidance model gives a possible solution to the occurrence and
persistence of chronic pain. This model states that when people react in a
fearful way to pain, they might avoid daily activities and become less active
in order to avoid the expected pain or possible injury. This inactivity
together with depression and perceived disability has a negative influence on
pain intensity. With the further increase of pain, a vicious circle arises and
the pain becomes chronic. Eventually physical deconditioning could occur,
though the evidence supporting physical deconditioning in patients with chronic
pain is contradictory.
Another way to avoid pain or possible injury is to alter the way daily
activities are performed. There is evidence that patients with CMP walk more
slowly and with a different walking pattern than healthy controls. We
hypothesize that this altered way of performing in walking could also be seen
in other daily activities such as stair climbing.
This altered way of performing daily activities in patients with CMP is likely
to be less efficient, i.e. resulting in a higher energy consumption. This
higher energy expenditure during daily activities could also explain the
fatigue reported by patients with CMP and the contradictory findings regarding
the presence or absence of deconditioning.
Study objective
The main purpose of the current study is to evaluate whether patients with CMP
have a higher energy expenditure during walking a prescribed distance or
climbing a prescribed number of stair steps than healthy volunteers.
Study design
The differences in energy expenditure between patients with CMP and healthy
volunteers are explored in a cross-sectional study.
Study burden and risks
Participants visit the hospital once. They have to fill in several
questionnaires regarding daily activities and for patients with CMP also
regarding pain and beliefs about pain. Participants perform two tests wearing a
gas analysing device, the Oxycon Mobile. They have to walk 500 meters at a self
chosen pace and climb 60 stair steps at a self chosen pace. If they feel tired,
resting is allowed. Performing these daily life activities is of no risk for
the subjects.
Universiteitssingel 40
6229 ER Maastricht
NL
Universiteitssingel 40
6229 ER Maastricht
NL
Listed location countries
Age
Inclusion criteria
Subjects with CMP:
1. Diagnosed with fibromyalgia or suffering from chronic low back pain (pain localized below the scapulae and above the gluteal folds for longer than three months)
2. Age between 18 and 65
3. The pain syndrome is not attributable to a recognizable, known specific pathology (e.g. infection, tumour, osteoporosis, fracture, structural deformity, inflammatory disorder (e.g. ankylosing spondylitis), radicular syndrome or cauda equina syndrome).
4. Ability to walk 500 meter without walking aids and walk 60 stair steps with the use of one handrail, resting during these activities is allowed
Healthy volunteers:
1. Age between 18 and 65
2. Ability to walk 500 meter without walking aids and walk 60 stair steps with the use of one handrail, resting during these activities is allowed
Exclusion criteria
Subjects with CMP
1. Use of β-blockers
2. Co morbidity hampering gas analyses, such as COPD or other lung conditions that require treatment by a lung specialist.
3. Pregnancy
4. Non-fluency in Dutch
Healthy volunteers:
1. Physical musculoskeletal pain
2. Use of β-blockers
3. Co morbidity hampering gas analyses, such as COPD or other lung conditions that require treatment by a lung specialist.
4. Pregnancy
5. Non-fluency in Dutch
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL39260.068.12 |