To determine differences in food cue reactivity between lean individuals and individuals with overweight. We will study behavioural (food choice, food intake, mood ratings) as well as physiological parameters (heart rate, skin conductance, saliva…
ID
Source
Brief title
Condition
- Other condition
- Appetite and general nutritional disorders
Synonym
Health condition
overgewicht
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Food-choice, ad libitum food-intake, mood, Saliva flow-rate, heart rate, skin
conductance responses.
Secondary outcome
Habituation response of heart rate and saliva flow-rate, alpha amylase activity
in saliva samples collected in one session
Background summary
Worldwide 1.5 billion adults are overweight. Overweight occurs when the intake
of energy exceeds energy expenditure. It has been suggested that overweight
people are more sensitive to sensory and rewarding effects of food, aspects
that mediate eating behaviour. Food odours can be considered as anticipatory
cues for the rewarding effects of food intake. Odours of foods with a high
energy content may predict higher reward value. Possibly, increased reward
sensitivity is related to a stronger bodily response and a stronger tendency to
choose high-energy food products after being exposed to high-energy food odours
(high food-cue reactivity). This may subsequently lead to overeating and
eventually to overweight. Differences in the behavioural and physiological
responses to (high-energy) food odours could explain why overweight people tend
to overeat and lean people do not.
Study objective
To determine differences in food cue reactivity between lean individuals and
individuals with overweight. We will study behavioural (food choice, food
intake, mood ratings) as well as physiological parameters (heart rate, skin
conductance, saliva production) in response to three different odour categories
(signalling non-food, high-energy food, low-energy food). We will study
physiological responses to non-food odours and pictures to determine an effect
of food cues, and rule out a more general increase in arousal of the autonomic
nervous system in overweight individuals.
Study design
Randomized controlled cross-over within-subject intervention study. Every
volunteer will participate in one screening session and six test sessions. In
each test session the volunteer will be exposed to an ambient odour and will be
tested for physiological and behavioural measures that reflect food cue
reactivity.
Intervention
ad libitum food intake
exposure to ambient odours
Study burden and risks
This study is non-therapeutic. Participation with this study is associated with
a negligible burden and risk. Compared to other studies the burden can be
considered as low. The study includes six site visits (3 x hungry, 3 x
satiated) plus a screening session.
Bomenweg 2
WAGENINGEN 6703HD
NL
Bomenweg 2
WAGENINGEN 6703HD
NL
Listed location countries
Age
Inclusion criteria
Female
BMI between 18.5-25 kg/m2 (lean) or above 27 kg /m2 (overweight)
18-55 years of age
Exclusion criteria
- Food preference inconsistent with food odours used in the study
- Food sensitivity/allergy for food products used in the study
- Vegetarian
- Impairments in sight, hearing or hand movements that interfere with following the instructions
- Impairments in smelling or swallowing
- (Post)menopausal
- Pregnant in the past 6 months
- Breast feeding
- History of psychiatric, neurologic or physical illness/abnormalities that might influence eating behaviour or body weight (e.g. eating disorder, endocrine illness, gastro-intestinal illness)
- Use of medication that interferes with the aim of the study (e.g. psychoactive, anti-obesity)
- Brain trauma (loss of consciousness for more than 10 minutes)
- Addiction (recent or current)
- Smoker
- Participants that, in the opinion of the researcher, are not able to understand test instructions and procedures
- Staff member of the division of Human Nutrition at Wageningen University
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL40419.081.12 |