To quantify renal tumour motion using MRI.
ID
Source
Brief title
Condition
- Renal and urinary tract neoplasms malignant and unspecified
- Renal disorders (excl nephropathies)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Quantify renal tumour movement with MRI.
Secondary outcome
Determine the reproducibility of a renal tumour position during multiple
breath-holds.
Background summary
Non-metastasised renal tumours are currently treated with a whole or partial
nephrectomy. Radiotherapy is a non-invasive alternative treatment for renal
tumours. To avoid normal tissue damage during radiotherapy image-guidance with
good soft tissue contrast, only available in MRI, should be present. An MRI
accelerator, which is a combination of a radiotherapy treatment machine and an
MRI scanner, will be clinically available in about two years. An MRI
accelerator will enable to detect the tumour position real-time during the
radiotherapy treatment and will, non-invasively, be able to spare much healthy
kidney tissue. To design a treatment on the MRI-accelerator the tumour motion
should be known.
Study objective
To quantify renal tumour motion using MRI.
Study design
Observational study to investigate kidney and renal tumour motion.
Study burden and risks
Patients will undergo one MRI scan of approximately 30 minutes. No contrast
will be administered. The use of MRI is after proper screening free of any
risks. For the patients included in the study there is no individual benefit.
Heidelberglaan 100
3584CX Utrecht
NL
Heidelberglaan 100
3584CX Utrecht
NL
Listed location countries
Age
Inclusion criteria
- Renal leasion
- Written informed consent
Exclusion criteria
- Patients who meet exclusion criteria for MRI following the protocol of the department of radiology UMCU.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL35291.041.11 |