The primary objective of the present study is to study influence of different types of electrical stimulation on functional hand opening. The secondary objective of the study is to gain more insight in muscle activation patterns and kinematics…
ID
Source
Brief title
Condition
- Central nervous system vascular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study parameter of the present experiment is the Box and Block test
which measures hand function of stroke patients. This functional measure is
used to evaluate the influence of different types of electrical stimulation on
functional hand opening.
Secondary outcome
Secondary study parameters are muscle activation patterns (MAP) measured with
electromyography and kinematics during reach-to-grasp movements.
Background summary
The majority of stroke patients have to cope with impaired arm and hand
function after a stroke. Post stroke rehabilitation training aims to regain
(partly) lost functions by stimulation of restoration or promoting
compensational strategies, in order to increase the level of independence.
During rehabilitation training movements are practiced preferably with high
intensity, in a task-oriented way, with an active contribution of the stroke
survivor in a motivating environment. An effective training modality that is
commonly applied in post stroke upper extremity rehabilitation training is arm
support by means of gravity compensation. In order to increase functional
abilities of the affected arm, hand function should also be trained. A
promising technique to train hand function, or more specifically hand opening,
after stroke is electrical stimulation of wrist and finger extensors and thumb
abductors/extensors.
Study objective
The primary objective of the present study is to study influence of different
types of electrical stimulation on functional hand opening. The secondary
objective of the study is to gain more insight in muscle activation patterns
and kinematics during functional reach-to-grasp movements.
Study design
The study has a cross-sectional design, with one measurement session (T1) for
healthy elderly and two sessions (T1 and T2, spaced approximately 3 months
apart) for stroke patients.
Intervention
During the T2 experiment, stroke survivors will perform the Box and Block Test
(BBT) in three conditions:
1. Without electrical stimulation
2. With single channel electrical stimulation to support hand opening.
3. With multi channel electrical stimulation to support hand opening.
Study burden and risks
The risks for the subjects are limited to a minimum, since the movement tasks
represent functional and familiar arm movements and are performed only within
the scope of the subject*s ability while he/she is seated. In addition, the
measurements used in this study (EMG, kinematics, functional scales) are all
noninvasive and involve no risks to the patients in any way. During the T2
measurement stroke patients receive electrical stimulation applied by surface
electrodes. During long term electrical stimulation skin irritation is
possible. The risk for skin irritation is minimized by stimulation with as low
as possible amplitudes and minimizing the time during which the stimulator is
active.
Participation of a subject in this experiment has no direct benefit for
him/her, other than expanding knowledge about underlying mechanisms of motor
control of the arm and hand and aiding in development of sophisticated
multichannel electrical stimulation algorithms.
Roessinghsbleekweg 33B
7522 AH Enschede
NL
Roessinghsbleekweg 33B
7522 AH Enschede
NL
Listed location countries
Age
Inclusion criteria
Inclusion criteria for stroke patients are:
1. a history of a single unilateral stroke in the medial cerebral artery (MCA) region resulting in single-sided hemiparesis.
2. the onset of the stroke was more than six weeks ago
3. the ability to voluntarily generate 20 degrees excursions in the plane of elevation (horizontal ab-/adduction) and elevation angle (ab-/adduction, ante-/retroflexion) of the shoulder joint.
4. the ability to voluntarily generate an excursion of 20 degrees of elbow flexion/extension,
5. the ability to voluntarily extend the wrist 10 degrees from neutral flexion/extension
6. adequate cognitive function to understand the experiments, follow instructions, and give feedback to the researchers.;Inclusion criteria for healthy elderly are:
1. ability to decide whether or not to participate in the experiment and sign an informed consent.
Exclusion criteria
Exclusion criteria for both stroke patients and healthy elderly are:
1. a fixed contracture deformity in the affected upper limb was present
2. pain as a limiting factor for the subject's active range of motion
3. age below 40 years
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL34868.044.10 |
| OMON | NL-OMON28137 |