The goal of this study is to investigate the long term results after transurethral treatment of infravesical obstruction in boys with respect to LUTS, incontinence, urinary tract infections, coping style and quality of life, and possible…
ID
Source
Brief title
Condition
- Urethral disorders (excl calculi)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
IPSS, urinary tract infections episodes, incontinence episodes, uroflowmetry,
post void residual
Secondary outcome
Micturition diary, retrograde ejaculation, coping style
Background summary
Transurethral resection of an infravesical obstruction in boys is frequently
performed in this hospital, about 200 times a year. Some patients have evident
narrowing of the urethra due to posterior urethral valves or bladder neck
hypertrophy, among other causes, while others have much more subtle
abnormalities. The long term outcome and complications of severe infravesical
obstruction are described in literature [1-5] However, results of treatment of
more subtle abnormalities is less well known.
Transurethral resection at young age may lead to complications, e.g. urethral
stricture. In adults retrograde ejaculation always occurs after bladder neck
incision, in children this is not known.
LUTS, incontinence en recurrent UTI*s, in combination with a urological
intervention at young age, may affect quality of life or coping style. Coping
style is the way a person reacts on problems in daily life. Coping style may
affect quality of life outcomes.
Study objective
The goal of this study is to investigate the long term results after
transurethral treatment of infravesical obstruction in boys with respect to
LUTS, incontinence, urinary tract infections, coping style and quality of life,
and possible complications of early transurethral treatment.
Study design
This is an observational cohort study using questionnaires and a non-invasive
bladdertest
Study burden and risks
Three questionnaires, a micturition diary (one day); non-invasive bladdertest
at the outpatient clinic
heidelberglaan 100
3584 cx utrecht
NL
heidelberglaan 100
3584 cx utrecht
NL
Listed location countries
Age
Inclusion criteria
Male sex
Age > 18 years
Transurethral treatment of infravesical obstruction between January 1986 and December 2010
Willing and able to participate in the study
• Signed informed consent
Exclusion criteria
Neurogenic bladder disorder
Congenital anomaly of the penis, like hypospadias or epispadias
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL35634.041.11 |