To investigate the effectiveness of Mindfulness Based Compassionate Living (MBCL) in recurrent depressive patients.
ID
Source
Brief title
Condition
- Mood disorders and disturbances NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Primary outcome measure is depression symptoms according to the Beck Depression
Inventory (BDI-II).
Secondary outcome
Secondary outcome measures will be: mindfulness skills (Five Facet Mindfulness
Questionnaire: Baer et al., 2006), self-compassion (Self-Compassion Scale:
Neff, 2003), rumination (Ruminative response scale: Raes et al, 2003) and
quality of life (WHO-QCL, World Health Organisation, 2004).
Background summary
Since a few years, Mindfulness Based Cognitive Therapy has been used as
treatment for patients suffering from recurrent depression. Though a number of
studies show that MBCT is effective in this population (Baer et al., 2011) and
MBCT reduces the chances of relapse/recurrence in recurrent depressive patients
(Piet et al., 2011), the chance of a new depression developing after end of
treatment is still considerable (53%). Ergo, there is room for improvement.
Especially the development of a non-judging or compassionate attitude towards
all experience seems to mediate the treatment effect. It is therefore our
expectation that a follow-up intervention that focuses specifically on
self-compassion could prove very useful in elaborating on the effects of MBCT.
The research question of this research is therefore: what is the effect of
compassion training in people suffering from recurrent depression who have
already done an MBCT training?
Study objective
To investigate the effectiveness of Mindfulness Based Compassionate Living
(MBCL) in recurrent depressive patients.
Study design
A randomized, controlled trial. After a baseline interview, patients will be
assigned to either MBCL and Treatment as Usual (TAU) or TAU alone. The control
group will receive MBCL after 6 months. The two groups will be followed for
another 6 months.
Intervention
Mindfulness Based Compassionate Living, added to TAU.
Study burden and risks
For the patients assigned to either the MBCL condition or the control group,
the burden will be to attend the 8-week training programme of the MBCL. The
participants are expected to do homework at home every day. They are also asked
to be present for a baseline interview (1 hour), followed by 2 follow-up
measures consisting of questionnaires for the MBCL condition and 3 follow-up
measures for the control group (who receive TAU for 6 months first).
Erasmuslaan 15
Nijmegen 6525 GE
NL
Erasmuslaan 15
Nijmegen 6525 GE
NL
Listed location countries
Age
Inclusion criteria
Adults (18-65) suffering from recurrent depression (1 or more, acc. to DSM-IV criteria) and who have previously participated in a Mindfulness based Cognitive Therapy training.
Exclusion criteria
1. One or more previous (hypo)manic episodes according to DSM-IV criteria
2. Primary psychotic disorder
3. Clinically relevant neurological conditions or somatic conditions that could be related to the depression
4. Current alcohol and/or drug abuse
5. Use of high dosages of benzodiazepines
6. Recent electro convulsive therapy (less than 3 months ago)
7. No prior experience with MBCT.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL44457.091.13 |