To examine whether BPD SUD patients have more overregulation of emotionsthan BPD or SUD patients only and to examine whether overregulation In BPD SUD patientsIs moderated by dissociation. And to examine whether PTSD patients with SUD have…
ID
Source
Brief title
Condition
- Personality disorders and disturbances in behaviour
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
A significant difference in overregulation will be expected between BPD SUD en
BPD patients and a significant difference in dissociation between
PTSD SUD and PTSD patients.
Borderline classification will be determined with the BPD-SI.
PTSD classification will be determined with the ZIL and VBE.
Alcohol or drugs addiction will be measured with a clinical Interview and
severity with the Europ-ASI, section III.
Dissociation will be measured with the DES and SDQ.
Secondary outcome
Dissociation will be measured with the DES and SDQ. The NLV will be
administered to
exclude low intelligence.
Affect Dysregulation which will be measured with the EI\/IOV-56 and
with the SIDES rev-sr.
Background summary
Affect or emotion dysregulation is known as a core component in Borderline
Personality Disorder (BPD) and trauma-post traumatic stress disorder (PTSD).
Affect dysregulation consists of two forms: underregulation and overregulation.
Under regulation has been defined as an
impairment of modulation of affect. Overregulation has been defined as a
suppression or
repression of affective awareness or expression. Deficits in emotion regulation
are also found
in substance-dependent patients (SUD).
Although overregulation In substance use disorders and borderline personality
disorders is
researched separately, overregulation In patients with both features is largely
unstudied. In
the present study we expect to find more overregulation symptoms in patients
with both
disorders than in patients with a single disorder (BPD or SUD).
Furthermore, although PTSD symptoms appear to affect many individuals who have
SUD,
the role of dissociation In PTSD SUD patients Is largely unknown. More
knowledge about the
role of dissociation In PTSD will add to the development of effective
treatment. We expect to
find more symptoms of dissociation In patients with both disorders than In
patients with a
single disorder (PTSD or SUD).
Measures of dissociation were also used to assess whether the relationship
between SUD
and overregulation Is moderated by dissociation. Although earlier research has
Indicated that
dissociation seems to play a moderating role In emotion regulation problems
Including
overregulation, Its specific role In BPD SUD patients remained unclear. We
expect to find a
moderating role of dissociation in BPD SUD patients.
Measures of affect dysregulation were used to assess whether the relationship
between SUD
and dissociation Is moderated by affect dysregulation. We expect to find a
moderating role of
affect dysregulation in PTSD SUD patients.
Study objective
To examine whether BPD SUD patients have more overregulation of emotions
than BPD or SUD patients only and to examine whether overregulation In BPD SUD
patients
Is moderated by dissociation. And to examine whether PTSD patients with SUD
have more
dissociation than PTSD patients without SUD or SUD patients only. Further It
will be studied
whether the dissociation symptoms in PTSD SUD patients are moderated by affect
dysregulation.
Study design
cross sectional design.
Study burden and risks
patients will be tested Individually In one session of approximately of
2X45 minutes, with a short break of fifteen minutes in between. Because of the
non-invasive
character of the interviews and questionnaires and because testing Is part of
usual care, the burden and
risks associated with participation are considered low.
Prins Constantijnweg 131
Rotterdam 3066TA
NL
Prins Constantijnweg 131
Rotterdam 3066TA
NL
Listed location countries
Age
Inclusion criteria
BPD SUD patients:
• Patients between 18 - 60 years, referred to Bouman GGZ
• Diagnosis of borderline personality disorder, confirmed by BPD-SI interview
• Diagnosis of a substance use disorder (alcohol or drugs), confirmed by a clinical interview
• Willing to participate in this project
• Abstinent for alcohol or drugs by at least one week
• Understand Dutch language;PTSD patients:
Same criteria as BPD SUD patients, except diagnosis of BPD. Instead, diagnosis of PTSD, confirmed by ZIL and VBE self-report lists.;SUD patients:
• Patients between 18-60 years, referred to Bouman GGZ
• Diagnosis of substance use disorder (alcohol and/or drugs), confirmed by a clinical interview
• Willing to participate in this project
• Abstinent for alcohol or drugs by at least one week
• Understand Dutch language
• Absence of DSM-IV borderline personality disorder, confirmed by BPD-SI interview
• Absence of DSM-IV PTSD, confirmed by ZIL and VBE.
Exclusion criteria
• Cognitive or mental impairments that make self-reports impossible
• Instable somatic illness that make self-reports impossible.
• Low intelligence
• Suicidality: severe suicide ideation or suicide planning
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL46569.101.13 |