To demonstrate that externally induced increases in epipalpebral pressure (EPP) relate to clinically significant increases in IOP, and to determine posture dependency of EPP. To determine the effects of protective goggles on EPP under these…
ID
Source
Brief title
Condition
- Glaucoma and ocular hypertension
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
IOP & EPP.
Secondary outcome
None.
Background summary
Glaucoma is the most frequent cause of irreversible blindness in the world.
Increased intra-ocular pressure (IOP) is the main risk-factor for development
(and progression) of glaucoma. It is currently unknown how much IOP is affected
during sleep with the pillow pressed against face and eyelids. The pressure
increase will be measured when subjects lie horizontally with their heads
resting normally on their own pillows, assuming a posture similar to during
sleep.
Study objective
To demonstrate that externally induced increases in epipalpebral pressure (EPP)
relate to clinically significant increases in IOP, and to determine posture
dependency of EPP. To determine the effects of protective goggles on EPP under
these conditions.
Study design
Experimental study.
Intervention
External force induced IOP increase.
Study burden and risks
Participants do not benefit from cooperating. Risks are considered to be
negligible, the burden is low.
Schiedamse Vest 180
Rotterdam 3011 BH
NL
Schiedamse Vest 180
Rotterdam 3011 BH
NL
Listed location countries
Age
Inclusion criteria
> 18 years of age.
Informed consent.
Exclusion criteria
History of IOP-reducing surgical intervention.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL45682.078.13 |