Validation of the modified Hetero Anamnestic screening instrument for Cognition (HAC-modified): a prognostic instrument in determining outcome after stroke.
ID
Source
Brief title
Condition
- Central nervous system vascular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Spouses/close relatives: HAC-modified (10-15 minutes)
Patients: cognitive examination (90 minutes)
- MMSE: orientation, serial seven
- ADS-8 wordtest
- Keyfindingtest
- Complex figure of Rey (part drawing)
- Stroop
- WAIS, similarities
- FAST (Frenchay Aphasia Screening Test), (language comprehension, expression)
- Digit symbol substitution test
Secondary outcome
Not applicable
Background summary
No validated instrument exists which assesses pre-stroke cognitive functioning.
Knowledge of pre-stroke cognitive problems is of importance, since the presence
of pre-stroke cognitive problems can influence post-stroke outcome. This
knowledge is also important for setting achievable rehabiliation goals.
Hence we created the modified Hetero Anamnestic screening instrument for
Cognition (HAC-modified), which is an improved version of the HAC, which is
more simplified and not validated. The HAC-modified is an instrument assessing
pre-stroke cognitive functioning through questioning spouses or close relatives
on possible problems on everyday activities of the stroke-patient.
Validation of the HAC-modified is mandatory to assess reliability in clinical
practice.
Study objective
Validation of the modified Hetero Anamnestic screening instrument for Cognition
(HAC-modified): a prognostic instrument in determining outcome after stroke.
Study design
Observational study
Study burden and risks
The burden for stroke patient and spouses/close relatives is low; testing takes
place only once and will take 90 minutens for stroke patients and 10-15 minutes
for spouses/close relatives.
There are no risks associated with partcipation, benefit and group relatedness,
since it is a onetime assessment of cognitive functioning during which no
invasive procedures take place and no therapeutic effect is intended.
Heijenoordseweg 5
Arnhem 6813 GG
NL
Heijenoordseweg 5
Arnhem 6813 GG
NL
Listed location countries
Age
Inclusion criteria
Patients:
- Age 18-80 years
- Diagnosed with stroke (hemorrhagic or ischemic)
- Stable neurological situation, at least 3 months post-stroke
- No, minor or severe cognitive problems
Healthy subjects
- Age 18-80 years
- No cognitive problems (younger population) or some cognitive problems (elderly population)
Exclusion criteria
Patient
- Severe communication problems
- Mental retardation
- Other disease (except stroke) possibly affecting cognitive functioning (neurologic, psychiatric or internal disease)
- Neuropsychological testing less than 3 months ago
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL43934.072.13 |