Research with human participants

Overview of medical research in the Netherlands

The effect of CMPX-2023 in the transplant model of psoriasis; in which a psoriatic lesion is induced in non-lesional skin transplanted onto immune-deficient (BNX) mice by injecting super-antigen activated peripheral blood cells intra-dermally into the transplant.

Published:
Last updated:

Is CMPX-2030 effective in the transplant model of psoriasis

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Ethical review
Approved WMO
Status
Recruitment stopped
Health condition type
Other condition
Study type
Observational invasive

ID

NL-OMON38996

Source

ToetsingOnline

Brief title

The effect of CMPX-2023 in the transplant psoriasis model

Condition

  • Other condition
  • Autoimmune disorders
  • Epidermal and dermal conditions

Synonym

psoriasis

Health condition

een onderzoek naar werking van een middel in een model

Research involving

Human

Sponsors and support

Primary sponsor :
Complix
Source(s) of monetary or material Support :
Industry

Intervention

Keyword :
psoriasis, skin, therapies, transplant

Outcome measures

Primary outcome

NA

Secondary outcome

NA

Background summary

Client wishes to know if CMPX-2023 is effective in the transplant model of
psoriasis

Study objective

Is CMPX-2030 effective in the transplant model of psoriasis

Study design

Blood and skin biopsies are taken from patients with psoriasis vungaris

Study burden and risks

NA

Public
Complix

Technologiepark 4
Gent 9051
BE
Scientific
Complix

Technologiepark 4
Gent 9051
BE

Listed location countries

Netherlands

Age

Adults (18-64 years)
Elderly (65 years and older)

Inclusion criteria

Patients with light to mild psoriasis vulgaris

Exclusion criteria

-Volunteers cannot be treated systemically (for psoriasis)
Volunteers cannot have UV/light therapy
Volunteers cannot be taking immune-modulating drugs for other diseases
Volunteers should not have problems with the Köbner phenomenom.
-Volunteers with atopic dermatitis/eczematous skin conditions.
-Volunteers cannot be pregnant

Design

Study type :
Observational invasive
Masking :
Open (masking not used)
Control :
Uncontrolled
Primary purpose :
Other

Recruitment

NL
Recruitment status
:
Recruitment stopped
Start date (anticipated) :
Enrollment :
22
Type :
Actual

Approved WMO
Date :
Application type :
First submission
Review commission :
METC Leiden-Den Haag-Delft (Leiden)

metc-ldd@lumc.nl

Followed up by the following (possibly more current) registration

No registrations found.

Other (possibly less up-to-date) registrations in this register

No registrations found.

In other registers

Register ID
CCMO NL44176.098.13