In this study we will evaluate the diagnostic value of ultrasound in patients presenting without clinical observable synovitis at firstconsultation compared to de clinical diagnosis by the rheumatologist in the 12 month follow-up of this study.
ID
Source
Brief title
Condition
- Synovial and bursal disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
clinically observable arthritis by the rheumatologist within 12 months of
baseline measurement
Secondary outcome
NA
Background summary
Still 5% to 25% of the patients with rheumatoid arthritis present with joint
erosions at first consultation
despite the early referral facilities available nowadays. To improve patients
outcomes we need to
identify patients before the joint damage occurs. The Rotterdam Early Arthritis
Cohort criteria
improved early identification of patients without synovitis who developed later
on arthritis, but the
numbers needed to screen are high. The screening of 20 patients identified 3
patient who later on
developed arthritis.
Study objective
In this study we will evaluate the diagnostic value of ultrasound in patients
presenting without clinical observable synovitis at first
consultation compared to de clinical diagnosis by the rheumatologist in the 12
month follow-up of this study.
Study design
diagnostic design using a prospective cohort
Study burden and risks
The study will cost approximately 3 quarters of an hour extra time to scan the
hands, feet and shoulders with sonographie. Sonographie is a save method to
image the inside of the body by using sound waves. There are no known side
effects of this technique.
Dr Molewaterplein 50-60
Rotterdam 3000 CA
NL
Dr Molewaterplein 50-60
Rotterdam 3000 CA
NL
Listed location countries
Age
Inclusion criteria
inflammatory joint complaints of hand, foot or shoulder and in addition 1 other painful joint.
Exclusion criteria
Symptom duration> 12 months
Symptoms caused by:
Fibromyalgia
osteoarthritis
overuse
trauma
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL34428.078.10 |