Therefore, the aim of this study is to determine normal-values for esophageal pressure characteristics using a water-perfused high-resolution manometry catheter. Furthermore, we aim to compare pres
ID
Source
Brief title
Condition
- Gastrointestinal motility and defaecation conditions
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Resting pressure of the lower esophageal sphincter
Secondary outcome
LES relaxation pressure
Distal contractile amplitude
Background summary
Since the introduction of esophageal manometry in the mid 1950s many different
manometric systems have been introduced. The current gold-standard for
measuring esophageal pressure characteristics is the so-called high-resolution
manometry which refers to catheters with 1-cm manometric sensor spacing at the
position of the esophagogastric junction. Two different catheters are currently
available for clinical practice 1) catheters with water-perfused pressure
sensors, the so-called water-perfused catheters and 2) catheters with
solid-state pressure sensors, the so-called solid-state catheters. The current
classification for esophageal motility disorders as well as normal values for
high-resolution manometry have all been developed using solid-state catheters.
Normal-values for water-perfused high-resolution catheters are not available
and it is currently unknown whether pressure levels as measured by solid-state
catheters are different from water-perfused catheters.
sure levels as measured by solid-state catheters with water-perfused catheters.
Study objective
Therefore, the aim of this study is to determine normal-values for esophageal
pressure characteristics using a water-perfused high-resolution manometry
catheter. Furthermore, we aim to compare pres
Study design
A comparative study using solid-state high-resolution manometry catheters and
water-perfused high-resolution manometry catheters.
Study burden and risks
none
Meibergdreef 9
Amsterdam 1105 AZ
NL
Meibergdreef 9
Amsterdam 1105 AZ
NL
Listed location countries
Age
Inclusion criteria
Written informed consent
Minimum age: 18 years
Exclusion criteria
Gastrointestinal complaints
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL39310.018.11 |