Peri-operative Bloodloss after Aortic valve replacement
ID
Source
Brief title
Condition
- Coagulopathies and bleeding diatheses (excl thrombocytopenic)
- Cardiac valve disorders
- Cardiac therapeutic procedures
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Lab;C-reactief proteïne, leukocyten, platelets, hemoglobine, hematocriet,
creatinine, ureum, glomerular filtration fate**, CK, CKMB, troponine en
myoglobine
Bloodloss through Thoracicdrains
Amount of bloodtransfusion units
Secondary outcome
Length of stay on ICU
Re-interventions like Re-operatins as a Re-Sternotomia
Background summary
Every year in the Netherlands about 15,000 patients are undergoing cardiac
surgery. An increasing number of these patients are people who are undergoing
an aortic valve replacement. By this kind of surgery the use of a
heart-lung machine (ECC) is necesary. Thoraxic surgey is associated with blood
loss. The use of Heparin, and the heart lung machine can not prevented that
there is always some blood loss. However, blood loss, blood transfusion ,
mortality and morbidity are associated with them. For several years, there is a
possibility for using of an MECC system (Minimum extracorporeal Corporal
Circulation ). This system provides less hemodulutie and tubing contact with
the heart-lung machine. The dose of heparin can be reduced. The hypothesis is
that with a MECC hart-lungmachine perioperative blood loss can be reduced.
Study objective
Peri-operative Bloodloss after Aortic valve replacement
Study design
RCT
Intervention
Elective Aortic valve replacement
Study burden and risks
Not applicable
Haaksbergerstraat 55
Enschede 7513 ER
NL
Haaksbergerstraat 55
Enschede 7513 ER
NL
Listed location countries
Age
Inclusion criteria
Elective indicated AVR procedures
Exclusion criteria
Redo Hartsurgery
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL39386.044.12 |
| Other | nummer volgt nog |