To determine the incidence of posttraumatic osteoarthritis following distal radius fractures in a cohort of young non-osteoporotic patients and correlation with objective and subjective outcome measures.
ID
Source
Brief title
Condition
- Fractures
- Bone and joint therapeutic procedures
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The incidence of posttraumatic osteoarthritis.
Secondary outcome
Subjective outcome measures objectivied with the use of validated
questionnaires (PRWE, DASH, SF-36 and MHQ). Objective outcomes measured with
functional tests such as range of motion and gripstrength. Radiological
findings measured with X-rays.
Background summary
The development of posttraumatic osteoarthritis (PA) following distal radius
fractures (DRFs) has been commonly described. Direct and indirect joint impact
loading, soft tissue injuries, joint dislocation and intra-articular fractures,
increase the risk of progressive joint degeneration that causes PA. It is
thought posttraumatic osteoarthritis develops less in younger patients.
However, it might be more invalidating for a young non-osteoporotic patient to
develop posttraumatic osteoarthritis and loss of function following a distal
radius fracture than for an older patient. The extend of the loss of function
can be objectivied using functional measures, such as range of motion and grip
strength. Subjective measures to objectivy loss of function as experienced by
the patient can be performed using validated questionnaires. In this study, the
incidence of posttraumatic osteoarthritis following a distal radius fracture is
in young patients is determined. Also, the question arises what the correlation
between the existence of post traumatic osteoarthritis and the objective and
subjective outcome measures is following a distal radius fracture in young
patients.
Study objective
To determine the incidence of posttraumatic osteoarthritis following distal
radius fractures in a cohort of young non-osteoporotic patients and correlation
with objective and subjective outcome measures.
Study design
Descriptive cohort study
Study burden and risks
According to the international commission on radiological protection (ICRP) the
estimated risk for the radiological procedure (4 x-rays per subject) is
categorized asIIa, very low level of risk of radiogenic cancer, >0.2 and <2
mSv. In comparison to the * Rijks Instituut Voor Milieuhygiëne (RIVM)* , the
annual radiation dose in the Netherlands is 1.7 mSv. The number of visits is
once for the functional physical tests combined with the radiological
procedure. The physical discomfort during the functional tests and the
radiological investigation is minimal. The subject will be asked to sit still
for the radiological investigations for 4 times less than 1 minute.
Hanzeplein 1
Groningen 9713GZ
NL
Hanzeplein 1
Groningen 9713GZ
NL
Listed location countries
Age
Inclusion criteria
All patients treated in the period 2005 untill 2011 in the Medical Center Leeuwarden with a distal radius fracture of which the x-ray after the trauma and after 6 weeks is present in the archives of the Radiology Department. Men aged between the age 18-50 years and women between the age of 18-40 years at the time of presentation.
Exclusion criteria
Fractures treated more than 7 days following initial trauma, open fractures and preexistent osteoartritis.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| Other | Aangemeld bij NTR |
| CCMO | NL41587.099.13 |
| OMON | NL-OMON22608 |