Obtain information regarding the movement abilities and muscle strength in persons with several neuromuscular diseases, which can be used to develop a motion controlles arm suport for daily use and training of arm function.
ID
Source
Brief title
Condition
- Neurological disorders congenital
- Muscle disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Registration of single movements:
Shoulder abduction (straight arm), shoulder anteflexion (straight arm)
shoulder abduction (elbow flexed 90)
shoulder anteflexion (elbow flexed 90) shoulder internal rotation, shoulder
adduction in horizontal plane (Only with arm support)
Movement Registration of functional movements:
Bringing the hand to the mouth (active flexion and supination of the arm and
passive pronation)
Reaching to the left and right (active protraction of the scapula)
Pulling and pushing a light object on a table
EMG measures:
m. biceps brachii
- m. lateral deltoid
- m. triceps brachii
- m. trapezius descendens
- m. pectoralis major
Maximum Voluntary Contraction
- m. biceps brachii
- m. lateral deltoid
- m. triceps brachii
- m. trapezius descendens
- m. pectoralis major
Secondary outcome
fatigue (Numeric Rating Scale)
pain (Numeric Rating Scale) and location
Background summary
For the development of an empowered motion controlled arm support which can
assist in daily life and can be used for training, it is important to
- Assess limitations of the potential users
- Evaluate wishes and needs of potential users.
Previously the limitations and restrictions in daily activities have been
investigated with use of questionnaires (Title: Questionnaire regarding the
functioning of arms and hands-on disorder. Activity and participation level in
boys with Duchenne muscular dystrophy: CMO No.: 20081341)
UMC St Radboud and Maastricht University have laboratories in which human
movements can be analysed with VICON system and muscle activity can be recorded
with EMG.
Previously , we conducted a pilot for a draft protocol for motion analysis
testing. Title: Developing a measurement protocol for Upper Extremity Function
(UEF) in boys with Duchenne muscular dystrophy (DMD) (UEF study): CMO
Registration number: 2010/205
No ABR: NL32552.091.10
The present study is a continuation of these previous studies. The present
study uses an improved measurement protocol and is used for different potential
users. In addition to participants with Duchenne muscular dystrophy, the
limitations in arm function are evaluated in subjects with facioscapulohumeral
muscular dystrophy and limb girdle dystrophy.
Study objective
Obtain information regarding the movement abilities and muscle strength in
persons with several neuromuscular diseases, which can be used to develop a
motion controlles arm suport for daily use and training of arm function.
Study design
Observational explorative research according protocol:
registration of singular movements, functional movements and EMG registration
of the activities as a percentage of EMG of maximum voluntary contraction.
Study burden and risks
Due to the limited strength and possible poor overall physical condition of the
participants, participation can physically tiring.
The researchers are trained to indicate and ask for signs of fatigue and
overload and will implement breaks and finish the measurements if needed. The
burden is acceptable according to the researchers and the riscs are minimized
as shown in previous research.
Reinier Postlaan 2
Nijmegen 6584 CG
NL
Reinier Postlaan 2
Nijmegen 6584 CG
NL
Listed location countries
Age
Inclusion criteria
6 healthy control subjects
5-10 persons with confirmed diagnosis of spinal muscular atrophy
6 persons with confirmed diagnosis of fascioscapulohumeral dystrophy
6 persons with confirmed dignosis of limb girdle muscular dystrophy
All persons with a neuromuscular disease have impaired function of the upper extremity with a score on the Brooke scale of 3 or 4.
All persons are able to sit in a (wheel)chair with a low back rest
Exclusion criteria
Other diseases impairing arm function
inability to come to the movement analysis laboratory
inability to cooperate
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL39024.091.11 |