Disease activity, perianal involvement and lesion localisation are important influential parameters making sure no pregnancy is exactly alike and mode of delivery needs to be considered on an individual patient level.A complete anorectal function…
ID
Source
Brief title
Condition
- Anal and rectal conditions NEC
- Pregnancy, labour, delivery and postpartum conditions
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Anorectal function evaluation (questionaires, anal manometry, rectal compliance
and anal endosonography) before and six months after delivery.
Secondary outcome
The effect of child birth on anorectal function regarding
* Perianal involvement
* Complaints
* Disease activity
* Pregnancy outcome
Background summary
The European Crohn and Colitis organisation (ECCO) guidelines advise that
elective caesarean section is indicated for all woman with perianal involvement
even though the evidence suggesting harm from vaginal delivery in woman with
inactive disease is scarce.
Disease activity, perianal involvement and lesion localisation are important
influential parameters making sure no pregnancy is exactly alike and mode of
delivery needs to be considered on an individual patient level.
A complete anorectal function evaluation (AFE) in relation to degree of
(perianal) involvement prior to delivery could be a tool in predicting
functional sphincter outcome and incontinence after vaginal delivery in
patients with Crohn*s disease and Colitis Ulcerosa. Thereby contributing to the
decision making process surrounding what mode of delivery is the most
appropriate for each patient.
Study objective
Disease activity, perianal involvement and lesion localisation are important
influential parameters making sure no pregnancy is exactly alike and mode of
delivery needs to be considered on an individual patient level.
A complete anorectal function evaluation (AFE) in relation to degree of
(perianal) involvement prior to delivery could be a tool in predicting
functional sphincter outcome and incontinence after vaginal delivery in
patients with Crohn*s disease or Colitis Ulcerosa. Thereby contributing to the
decision making process surrounding what mode of delivery is the most
appropriate for each patient.
Study design
Descriptive prospective study.
Study burden and risks
No additional risks are associated with participation for the healthy controls,
patients with M Crohn or for patients with Colitis Ulcerosa.
In providing the best possible care it is of the utmost importance to know what
mode of delivery is best suited for each individual patient.
De Boelelaan 1118
Amsterdam 1081 HZ
NL
De Boelelaan 1118
Amsterdam 1081 HZ
NL
Listed location countries
Age
Inclusion criteria
* Age 18 years and older
* Informed Consent (IC)
* Pregnancy
* Healthy controls, patients with Colitus Ulcerosa, patients with M Crohn
Exclusion criteria
* Refusal of participation
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL42002.029.12 |