The main objective is to find markers for arrhythmia vulnerability in patients with end stage heart failure.
ID
Source
Brief title
Condition
- Cardiac arrhythmias
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Measurements of the electrophysiological, structural and (immuno) histological
characteristics of mature ventricular cardiomyocytes and serum markers.
Secondary outcome
Potential electrical markers and biomarkers for arrhythmia vulnerability.
Background summary
In patients with congestive heart failure (CHF) a major cause of mortality is
sudden cardiac death (SCD). A large amount of studies has been conducted to
investigate determinants of increased susceptibility to SCD, yet the mechanism
remains obscured.
Therefore this study will focus on the analysis of electrophysiological,
structural, (immuno) histological parameters and serum proteins in patients
with end stage heart failure to determine markers for arrhythmia vulnerability.
Study objective
The main objective is to find markers for arrhythmia vulnerability in patients
with end stage heart failure.
Study design
This is an observational study.
Study burden and risks
Inclusion in the study does not bring additional burden or risk for these
patients.
Meibergdreef 9
Amsterdam 1105AZ
NL
Meibergdreef 9
Amsterdam 1105AZ
NL
Listed location countries
Age
Inclusion criteria
Patients will be included if they are over 18 years and under 80 years and able to give informed consent.
Patients with end stage heart failure undergoing LVAD implantation.
Exclusion criteria
Under 18 and over 80 years
The inclusion criteria includes only the study population.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL39545.018.12 |