To investigate the long term stability (> 5 yrs) in patients treated with mandibular distraction osteogenesis (MDO) for correction of a Class II-occlusion. Hypotheses:1) MDO is a technique for mandibular lengthening with comparable stability to…
ID
Source
Brief title
Condition
- Other condition
- Bone disorders (excl congenital and fractures)
- Bone and joint therapeutic procedures
Synonym
Health condition
evaluatie stabiliteit van chirurgische interventie
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Main study parameters
Cephalometric analysis will be carried out on the pre-operative,
post-distraction and these radiographs. The following measurements will be
made:
* SNB-angle: sella/nasion-mandibular point B
* SN-MP: sella/nasion- mandibular plane
* Point B in respect to x and y-axis
* x-axis= SN, y-axis: perpendicular line to x-axis
Primary parameter is to establish horizontal mandibular relapse. This is
defined as change of position of point B in a horizontal (mandibular) plane.
Secondary outcome
N/A
Background summary
Mandibular distraction osteogenesis (MDO) is an alternative technique for
mandibular lengthening to the conventional bilateral sagittal split osteotomy
(BSSO) in patients with a mandibular hypoplasia. Both methods are surgical
procedures that are performed in a combined surgical-orthodontic treatment plan.
Longterm skeletal stability after BSSO has been studied en reported in the
literature for the conventional method. Influencing factors as the amount of
advancement, type of fixation, mandibular plane (high- and low angle patients),
surgical skills and bone, muscular and soft tissue have been reported.
An advantage of MDO is the possibility to achieve a larger amount of
lengthening (>10mm), which is required in some patients with an severe
mandibular hypoplasia, e.g. syndromic patients or children. Therefore, the
chances of skeletal relapse might be increased in these patients.
Short- and middleterm stability of MDO in comparison to the BSSO-technique
shows similar skeletal stability. However, to our knowledge the longterm
stability (at least more than 5 years) of MDO has not been studied or reported
in the literature. Since this technique has become a more routine procedure in
orthognatic surgery, it is of importance to establish the longterm stability
and amounts of possible skeletal relapse. These results could lead to
recommendations to the surgical protocol and could be beneficial to future
patients.
Study objective
To investigate the long term stability (> 5 yrs) in patients treated with
mandibular distraction osteogenesis (MDO) for correction of a Class
II-occlusion.
Hypotheses:
1) MDO is a technique for mandibular lengthening with comparable stability to
other commonly used techniques (BSSO)
2) High-angle patients, lengthening > 10 mm and female patients (>38°) are more
at risk for relapse than low-angle patients, lengthening < 10mm and male
patients
Study design
This is a retrospective, cephalometric study to determine skeletal stability of
mandibular distraction performed between 1999-2006. Patients will be recalled
for a cephalometric radiograph. Cephalometric tracing will be carried out using
advanced software and manual tracing by two investigators.
Study burden and risks
In our opinion the nature and extrent of burden and associated risk is minimal.
The longterm stability (at least more than 5 years) of mandibular distraction
osteogenesis has not been studied or reported in the literature. Since this
technique has become a more routine procedure in orthognatic surgery, it is of
importance to establish the longterm stability and amounts of possible skeletal
relapse. These results could lead to recommendations to the surgical protocol
and could be beneficial to future patients.
De Boelelan 1118
Amsterdam 1087 HV
NL
De Boelelan 1118
Amsterdam 1087 HV
NL
Listed location countries
Age
Inclusion criteria
Mandibular hypoplasia treated with mandibular distraction osteogenesis
Exclusion criteria
Follow-uptime shorter <5 years
Other orthognatic surgery (genioplasty, sagittal split osteotomy)
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL40744.029.14 |