To investigate whether applying small changes to the gait pattern of patients with osteoarthritis lead to a reduction of the knee adduction moment in both the short term and long term.
ID
Source
Brief title
Condition
- Bone and joint injuries
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
knee adduction moment peak and impulse values
Secondary outcome
- Degree of osteoarthritis in the knee (score based on the questionnait "Knee
injury and Osteoarthritis Outcome Score" (KOOS));
- Mobility level (score based on the questionnaire *Physical Activity Scale for
the Elderly* (PASE));
- Muscle force of the major muscle groups for the extension and flexion of the
leg, hip and ankle;
- Muscle activation patterns measured using electromyography (EMG).
Background summary
Osteoarthritis is a chronic and irreversible degeneration of the joint
cartilage. The knee load (knee adduction moment) seems to have an important
role in the development and progression of medial tibiofemoral osteoarthritis.
A reduction of the knee load could slow down the joint cartilage degeneration
and reduce the physical complaints. A reduction of the knee load can be
achieved using a knee brace or shoe insoles. However, the adherence of the
patients to wearing these orthopedic aids is known to be limited. An
alternative approach in reducing the knee adduction moment without the use of
external walking aids is gait retraining. By applying subtle changes to the
existing gait pattern, both the direction and the magnitude of the forces that
act upon the knee can be changed.
Study objective
To investigate whether applying small changes to the gait pattern of patients
with osteoarthritis lead to a reduction of the knee adduction moment in both
the short term and long term.
Study design
Randomized Controlled Trial
Intervention
Participants are randomly assigned to either the experimental group or the
control group. Participants in the experimental group will receive lifestyle
advise regarding knee osteoarthritis. In addition, they will participate in a
maximum of 18 physical therapy sessions aimed at applying a gait retraining
strategy (medial thrust or trunk lean). The control group will only receive the
lifestyle advise.
Study burden and risks
The participant will follow a gait retraining program (max 18 sessions of 30
minutes) under the supervision of a physical therapist.
The participant will be measured in a movement laboratory (3 sessions of max 2
hours);
The participant will attend one presentation about lifestyle advise regarding
osteoarthritis;
At the start of the study one x-ray will be made of the knee;
The risks of possible physical injury are estimated to be minimal.
Ds. Th. Fliednerstraat 2
Eindhoven 5631 BN
NL
Ds. Th. Fliednerstraat 2
Eindhoven 5631 BN
NL
Listed location countries
Age
Inclusion criteria
-Age 50 years and older;
- Diagnosed with early stage tibiofemoral osteoarthritis (radiografically diagnosed or determined according to the American College of Rheumatology (ACR) guidelines;
- Kellgren-Lawrence grade 2 or 3;
- Ability to understand and read the Dutch language (this with regard to persons' ability to fill out questionnaires).
Exclusion criteria
-unable to walk without walking aid
-other orthopaedic or neurological diseases which can lead to functional limitations
-hip arthritis
-severe perceptual or cognitive limitations
-cardio or pulmonary diseases.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL47483.015.13 |