To noninvasively investigate the amount and (sodium and chloride) content of sweat in hypernatremic patients in the ICU.
ID
Source
Brief title
Condition
- Electrolyte and fluid balance conditions
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Sodium and chloride content in sweat and association with non-inflammatory
hyperthermia
Secondary outcome
None
Background summary
Non osmotic active storage of sodium was recently discovered is healthy
individuals on high salt diet. Critically ill patients in the ICU are due to
their illness treated with high salt in their intravenous fluids. There is a
relationship between hypernatremia and non-inflammatory hyperthermia. Whether
non osmotic active storage of sodium occurs in critically ill is unknown as
well as whether this influences their ability to sweat and therewith
thermoregulate.
Study objective
To noninvasively investigate the amount and (sodium and chloride) content of
sweat in hypernatremic patients in the ICU.
Study design
Prospective, observational, single center pilot study
Study burden and risks
The sweat test is non-invasive, currently in use in newborns and small children
(< 2 years) for the diagnostic purpose for cystic fibrosis. The test can be
done in bed, and takes 60 minutes.
Hanzeplein 1
Groningen 9700 RB
NL
Hanzeplein 1
Groningen 9700 RB
NL
Listed location countries
Age
Inclusion criteria
Adult patients admitted to the ICU of the UMCG
Hypernatremia (> 150 mmol/l)
> 3 days
Exclusion criteria
Age < 18 years
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL49873.042.14 |