The overall objective of the study is to quantify age-related changes in biomechanics and neural control of hand motor control and finger independence. Therefore, we will determine the finger interdependency during various finger tasks in terms of…
ID
Source
Brief title
Condition
- Muscle disorders
- Age related factors
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Biomechanics of the hand (tendon displacement and muscle activation) and finger
independence ( hand kinematics and individuation index) between young and
elderly.
Secondary outcome
Not applicable
Background summary
The human hand has evolved to be able to perform complex hand actions such as
prehension, gripping and pinching and is necessary in daily life for both fine
and gross hand movements. In elderly a gradual decline in the quality of hand
motor control is observed, which causes difficulty in performing everyday tasks
such as grasping and fine handicraft. To understand the underlying cause for
this decline in hand and finger movement, it is necessary to take all the
different systems, such as muscles, tendons and central motor control that
undergo changes with ageing and their mutual effect on one another into
consideration. In this experiment we will study both intermuscular mechanics
and the intermuscular motor drive to see their effects on independent finger
movement and the possible changes that may occur with ageing.
Study objective
The overall objective of the study is to quantify age-related changes in
biomechanics and neural control of hand motor control and finger independence.
Therefore, we will determine the finger interdependency during various finger
tasks in terms of movement, muscle functionality and muscle interactions in a
group of young healthy subjects and a group of healthy elderly.
Study design
Experimental comparison study of the neurophysical and muscular mechanics of
the hand for young and elderly subjects.
Study burden and risks
Ultrasound imaging has been used for over 20 years and has an excellent safety
record. It uses low-power sound waves and there are no direct risks from a
diagnostic ultrasound exam.Surface electromyography is a low-risk exam and
complications are rare and subjects will feel minimal discomfort during the
experiment. A motion capture technique is used, called the PowerGlove, where
the sensors are externally attached to the hand and the individual finger
joints and causes minimal discomfort as well. So, the risks for the subjects
involved in this project are minimal.
Reinier Postlaan 4
Nijmegen 6500 HB
NL
Reinier Postlaan 4
Nijmegen 6500 HB
NL
Listed location countries
Age
Inclusion criteria
- Young subjects: between 18-30 age, all subjects must be right-handed.
- Elderly subjects: between 65-80 years, all subjects must be right-handed and pass the mini-mental state examination (score 25 or higher on a total of 30 ).
Exclusion criteria
- Presence of wrist pain, previous hand or wrist trauma, previous surgery, and a history of inflammatory arthritis
- Experience with playing musical instruments for more than two years over the course of the last five years
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL49185.091.14 |