Assessing the effects of (anticipatory) stress associated with blood donation, by measuring basic psychological, physiological and hormonal parameters, on the donor*s haemostasis and the quality of the blood products.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Stressreacties
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The effects of stress on the donor*s haemostasis and the quality of the final
blood product will be examined (e.g. FVII, platelet activation).
Secondary outcome
Not applicable.
Background summary
Maintaining a constant supply of high-quality donor blood is essential for
society. However, stress reactions, elicited by a blood donation, might have an
effect on the final blood product. Therefore, insight is needed in the effects
of psychological and physiological stress reactions on the donor*s haemostasis
and the quality of the blood products.
Study objective
Assessing the effects of (anticipatory) stress associated with blood donation,
by measuring basic psychological, physiological and hormonal parameters, on the
donor*s haemostasis and the quality of the blood products.
Study design
Blood donors will be followed in the course of one blood donation.
Psychological, physiological, and hormonal parameters will be measured at
different points in the donation procedure. The effects of donation stress on
the donor*s haemostasis and the quality of donated blood products will be
investigated.
Study burden and risks
All measurements will be incorporated in one routine blood donation. This
avoids an extra visit to the blood bank and consequently decreases the burden
on the donor.
Plesmanlaan 125
Amsterdam 1066CX
NL
Plesmanlaan 125
Amsterdam 1066CX
NL
Listed location countries
Age
Inclusion criteria
- Eligible to be or become a blood donor, according to the eligibility rules of Sanquin
- Whole-blood donor (at measurement)
- Sufficiently able to read and write Dutch
Exclusion criteria
- Use of aspirin in the previous week
- Use of beta-blockers
- Use of corticosteroids
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL48314.018.14 |