The primary objective of this study is to assess the CV risk profile of Hindustanis without known diabetes mellitus (DM), hypertension, dyslipidemia or CV disease and evaluate the 10-year CV risk according to the Framingham risk score. Secondary…
ID
Source
Brief title
Condition
- Cardiac disorders, signs and symptoms NEC
- Glucose metabolism disorders (incl diabetes mellitus)
- Arteriosclerosis, stenosis, vascular insufficiency and necrosis
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Asymptomatic young Hindustanis have an increased CV risk profile, which demands
vigilance and early risk factor modification to prevent long-term CV events.
Secondary outcome
NVT
Background summary
Asian Indian migrants in the Western world are highly susceptible for ischaemic
heart disease (IHD). Until now, most IHD risk studies were performed in first
and second generation Asian Indian expatriates. For optimal prevention,
knowledge of the cardiovascular risk profile of younger generations is crucial.
Study objective
The primary objective of this study is to assess the CV risk profile of
Hindustanis without known diabetes mellitus (DM), hypertension, dyslipidemia or
CV disease and evaluate the 10-year CV risk according to the Framingham risk
score. Secondary objectives are to assess the value of screening in this
healthy subpopulation and to find unrecognised patients who should be treated
according to the Dutch guidelines.
Study design
On a mass cultural event in 2004, 2100 asymptomatic Hindustanis, age >18 yr,
were recruited. Ten percent of these population had a disease which needed an
treatment according the NHG-guidelines. In 2014 at a mass cultural event (Milan
Festival) the follow up study will continue to evaluate the incidicence of any
cardiovascular event or treatment (medication) of diabetes, hypertension or
hypercholesterolaemia. There will also be a screening of new participants
(asymptomatic hindustanis >18 years) for risk factors of cardiovascular
diseases.
Study burden and risks
NVT
Albinusdreef 2
Leiden 2300 RC
NL
Albinusdreef 2
Leiden 2300 RC
NL
Listed location countries
Age
Inclusion criteria
Asymptomatic Hindustanis, age > 18 yr
Exclusion criteria
Hypertension, hypercholesterolaemia, diabetes or treatment (medication) for any of these.
Design
Recruitment
metc-ldd@lumc.nl
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL49460.058.14 |