We would like to reproduce results found in earlier studies en supplement them with ABR (BERA) testing. This is the primary goal of the research. For measuring auditory brainstem functions, ABR is the golden standard.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Het onderzoek heeft betrekking op normaal gehoor
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
brainstem evoked potentials
Secondary outcome
loudness scaling, stapedius reflex thresholds
Background summary
Auditory neural mechanisms in the brainstem are susceptible to change bij
changing the sound input to the ear. (Formby et al. 2003, 2007). This so called
neural gain is object of interest in this study. The mentioned change leads to
an altered loudness perception.
Study objective
We would like to reproduce results found in earlier studies en supplement them
with ABR (BERA) testing. This is the primary goal of the research. For
measuring auditory brainstem functions, ABR is the golden standard.
Study design
Test subjects will be compared with themselves. A subject will be asked to wear
earplugs for two weeks. Prior to this subjective and objective audiometry shall
be performed, including a loudness scaling. After wearing earplugs for two
weaks, the same tests shall be performed. Finally, after two more weeks
(without wearing earplugs) the test shall be repeated.
Intervention
wearing earplugs
Study burden and risks
The risks involved are transient if the occur. There will be three test
sessions, each 1,5 hours long. Earplugs will be made with a duration of 1 hour.
The test subjects do not have an advantage or disadvantage.
Hanzeplein 1
Groningen 9713 GZ
NL
Hanzeplein 1
Groningen 9713 GZ
NL
Listed location countries
Age
Inclusion criteria
Age >= 18 years
Normal hearing: thresholds up till 8 kHz 20 dB or less
Normal loudness tolerance
Normal middle ear function
Normal health
Geschreven informed consent
Exclusion criteria
• Otological history
• Tinnitus
• Hyperacusis
• Otological conditions prohibiting occlusion of the ear canal
• Hearing Loss
• Unobtainable ART, e.g. due to a flat tympanogram
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL49936.042.14 |