Investigate if preoperative IMT affects the incidence of postoperative pneumonia after esophageal resection.
ID
Source
Brief title
Condition
- Respiratory tract infections
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Pneumonia
Secondary outcome
Respiratory muscle function, mechanical ventilation time, duration of hospital
stay.
Background summary
Esophageal resection is associated with a high incidence of postoperative
pneumonia. An earlier RCT showed, in patients undergoing cardiac bypass
surgery, that inspiratory muscle training (IMT) reduced postoperative pneumonia
with 50%. Whether IMT is also effective in other surgical patient groups, like
esophageal resection, is not yet investigated sufficiently.
Study objective
Investigate if preoperative IMT affects the incidence of postoperative
pneumonia after esophageal resection.
Study design
Multicenter randomised controlled trial.
Intervention
Preoperative inspiratory muscle training program which consists of 2x 30
breaths per day against resistance and is performed using an inspiratory muscle
trainer. Patients in de the control group don't undergo this training.
Study burden and risks
No adverse events have been reported during inspiratory muscle training.
Patients perform the training daily for 10 minutes, at home. There are 5 time
points for measurements, 3 of them during hospital admission, the other 2 as
much as possible during already planned hospital visits.
Heidelberglaan 100
Utrecht 3584 CX
NL
Heidelberglaan 100
Utrecht 3584 CX
NL
Listed location countries
Age
Inclusion criteria
Esophageal resection candidates
Exclusion criteria
Participating in a conflicting trial concerning esophageal resection
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL43194.041.13 |