The NEURONED-MS cohort study aims to facilitate prospective observational research in the field of multiple sclerosis (MS). This cohort will serve as the central part of several projects that will be organized to address various issues including:1.…
ID
Source
Brief title
Condition
- Central nervous system infections and inflammations
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Clinical and psychosocial data of all patients will be collected longitudinally
and prospectively on a regular basis.
Secondary outcome
not applicable
Background summary
The core objective in this project is to build up, maintain and yearly extend
an inception cohort of multiple sclerosis (MS) patients in the Netherlands.
This cohort is called NEURONED-MS. Most MS cohorts are recruited in tertiary
centers and as such not representative for the MS population as a whole. Due to
this selection bias information on physical, mental and social impact of the
disease might be distorted and adequate advice to policy makers is hampered.
Study objective
The NEURONED-MS cohort study aims to facilitate prospective observational
research in the field of multiple sclerosis (MS). This cohort will serve as the
central part of several projects that will be organized to address various
issues including:
1. the natural history of MS in the Netherlands
2. the psychosocial impact of MS on patients in the Netherlands
Study design
prospective inception cohort study
Study burden and risks
Patients will be asked yearly to complete a battery of questionnaires. The
questionnaire contains 27 pages. Administration time is approximately 30 min to
1 hour. Please see Appendix 2 in protocol for the content of the questions.
In addition, they are asked to participate in an interview by telephone, that
will take approximately half an hour.
The burden can be consideren minimal. Risks are negligible.
De Boelelaan 1089a
Amsterdam 1081HV
NL
De Boelelaan 1089a
Amsterdam 1081HV
NL
Listed location countries
Age
Inclusion criteria
Patients are eligible when they are diagnosed within the previous twelve months with MS (Polman et al., 2011), with dissemination in time and space (see protocol Appendix 3). Patients with Clinically Isolated Syndromes (CIS) may also be included if they fulfill 3 of the 4 Barkhof criteria for dissemination in space as per application of the revised McDonald criteria (Polman et al. 2011). Patients should be 18 years or older, and live in the Netherlands, and give written informed consent.
Exclusion criteria
not able to speak dutch, refusal to give informed consent
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| Other | CWO-nr. 11-08 |
| CCMO | NL36862.029.11 |