The primary objective of this study is to assess the association between pre-dialysis comprehensive geriatric assessment and early death or withdrawal from dialysis (
ID
Source
Brief title
Condition
- Other condition
- Dementia and amnestic conditions
- Age related factors
Synonym
Health condition
Kwaliteit van leven
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
To assess the association between pre-dialysis comprehensive geriatric
assessment and early death or withdrawal from dialysis (<6 months) after
initiation of dialysis in patients aged over 65 years
Secondary outcome
The secondary objective of this study is:
To assess the association between pre-dialysis GA and dialysis-related
complications in elderly patients
The tertiary objectives of this study are:
1. To describe the prevalence of geriatric syndromes in elderly patients
starting dialysis
2. To describe the changes in cognitive function and functional status in the
first 6 months after initiation of dialysis
3. To describe the association between pre-dialysis GA and quality of life,
functional and/or cognitive decline 6 months after initiation of dialysis
4. To describe the caregiver burden after initiation of dialysis
5. To compare the quality of life, functional and cognitive status at baseline
and s6 months later of elderly patients starting dialysis and elderly patients
choosing to forego dialysis treatment for whatever reason
6. To determine whether or not the success of dialysis and overall condition of
the elderly patient was properly estimated by the nephrologist before the start
of dialysis.
7. To assess how often falls occur within the six months period after
initiation of dialysis in elderly patients (>65 years of age),
8. To describe what the sequelae of falls are in terms of fall-related
injuries, emergerncy room visits, hospitalisation, fracures, care needs and
functional decline in elderly patients starting dialysis
9. To assess what the incidence is of osteoporosis in this patient cohort and
how the presence of osteoporosis contributes to injury risk after a fall (7.)
Background summary
The number of elderly patients with end-stage renal disease is increasing.
Nephrologists and patients are faced with the dilemma of whether or not they
should initiate dialysis. It is not yet known which older patients benefit from
dialysis treatment and in which patients the disadvantages outweigh the
advantages.
Study objective
The primary objective of this study is to assess the association between
pre-dialysis comprehensive geriatric assessment and early death or withdrawal
from dialysis (<6 months) in patients aged over 65 years
Study design
observational cohort study
Study burden and risks
There is no expected harm or benefit for the participating patients. The
estimated time for the two interviews is 80 minutes. Besides a walking test
will be applied (see E4)
Brennerbaan 130
Utrecht 3524 BN
NL
Brennerbaan 130
Utrecht 3524 BN
NL
Listed location countries
Age
Inclusion criteria
1. Patients over 65 years old who initiate dialysis in one of the participating dialysis centra
2. Patients over 65 years old who are eligible for dialysis (according to their nephrologist) in one of the participating dialysis clinics but deciding to withhold dialysis treatment
Exclusion criteria
Patients who do not understand or speak Dutch of English
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL47932.100.14 |