The aim of this study is to test the feasibility of a GXTT, combined with a SET in adults with ID, through completion rate of the GXTT and the SET, the subjective experience of the participants and determining if the VO2peak of the SET is likely to…
ID
Source
Brief title
Condition
- Other condition
- Neurological disorders congenital
- Cognitive and attention disorders and disturbances
Synonym
Health condition
verstandelijke beperking
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
What is the completion rate of performing both the GXTT and the SET in adults
(18-50 years) with ID?
Secondary outcome
• What is the subjective experience of adults (18-50 years) with ID of
performing familiarization procedure, the GXTT and the SET?
• Does the VO2peak measured with the GXTT is likely to reflect the VO2max in
adults with ID?
• Which baseline characteristics have a possible influence on the feasibility
of the GXTT combined with the SET?
Background summary
Cardiorespiratory fitness is an important component of physical fitness and
refers to the ability of the circulatory and respiratory systems to supply
oxygen to working muscles during physical activity and is measured by the
maximum volume of oxygen (VO2max), that can be transported per minute. The gold
standard for measuring cardiorespiratory fitness is a maximal cardiorespiratory
exercise test, like the Graded Maximal Treadmill Test (GXTT). For people with
an intellectual disability, it is unknown if the results of a maximal
cardiorespiratory exercise test reflect their maximal capacity. The scores of a
GXTT can be compared with a Supramaximal Exercise Test (SET) to determine
whether the attained VO2 during the GXTT is indeed the true VO2max. It is
unknown if the GXTT and the SET are feasible for adults with ID.
Study objective
The aim of this study is to test the feasibility of a GXTT, combined with a SET
in adults with ID, through completion rate of the GXTT and the SET, the
subjective experience of the participants and determining if the VO2peak of the
SET is likely to reflect the VO2peak of the GXTT.
Study design
This is a study with a crosssectional observational design
Study burden and risks
The participants will perform a GXTT and a SET, with a heart rate and breath
analyses. Due to the nature of the tests only participants who can sign their
own informed consent will be included in this study. The safety of executing
these two tests is screened on beforehand and checked with a physician in case
of doubt. If safety is not sufficiently confirmed a participant will be
excluded. To optimize maximal testing results, the participants will go through
a three-step familiarization process before performing the treadmill tests, to
ensure the participants are able to perform with maximal effort. Only when a
participant is familiar with the current step will the next step be introduced.
Additional familiarization sessions will be scheduled for each step for
participants who need more practice sessions. For safety, the tests will be
administered by a physical therapist, oxygen saturation and heart rate will
constantly be monitored during testing and the participant can hold on a bar
during testing. Since this study tests the feasibility of the GXTT and SET for
adults with ID, this study could not be tested in other populations.
's-Gravendijkwal 230
Rotterdam 3015 CE
NL
's-Gravendijkwal 230
Rotterdam 3015 CE
NL
Listed location countries
Age
Inclusion criteria
•Between 18-50 years old
•Diagnosed with an intellectual disability (ID)
•Able to follow instructions regarding testing
•Able to sign informed consent according to the participants* behavioral therapist
•Completed a Physical Readiness Questionnaire (PAR-Q). If one of the question is answered with *YES*, a medical doctor will be consulted for medical clearance to participate.
Exclusion criteria
•Significant ambulatory problems that would inhibit treadmill walking
•Taking medications that could affect normal physiological responses to exercise
•Medical contraindications to exercise
•Heart-rate-altering medications
•Congenital or atherosclerotic heart disease, metabolic disease,
•Respiratory disorders including asthma
•Not obtaining medical clearance
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL51441.078.14 |