The main objective of the current study is investigating whether AN patients and healthy controls differ in how they experience (estimate) the size of their abdomen before and after multisensory input is provided (we will compare size estimation…
ID
Source
Brief title
Condition
- Eating disorders and disturbances
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary study parameter in the current study is the error in size
estimation of the size of the abdomen before and after providing multisensory
input. By subtracting these two scores a difference score emerges. This allows
for testing whether size estimation changed from pre to post multisensory
input, and whether AN patients and healthy controls differ on this variable. In
addition, participants will also estimate the size of control body parts
(shoulders, hips, height), we do not expect any differences in size estimation
error from pre to post multisensory stimulation.
Secondary outcome
The first secondary study parameter is again the difference in size estimation
error from pre to post multisensory stimulation. However, not only group
differences will be assessed, we will also investigate whether size estimation
errors differ between synchronous and asynchronous multisensory stimulation.
Based on our previous study we do not expect differences between providing
multisensory input synchronously compared to asynchronously.
The second secondary study parameter is the error in size estimation during the
follow up measurement. This follow up error can be compared to pre and post
size estimation errors. This will indicate whether within either group the
change in body size experience after multisensory input is persistent over
time.
Background summary
Anorexia Nervosa (AN) is one of the most invasive psychosomatic disorders with
a relatively high mortality rate. In order to ensure successful treatment it is
crucial to understand the underlying mechanisms of AN. One of the central
symptoms of AN is a disturbed experience of the own body. To date, not all
aspects of this so-called body image disturbance have been investigated fully.
Though, research shows that body image disturbances appear to be the key to
full recovery of AN. Therefore in the current study we will focus on
multisensory input and body size experience.
In one of our previous studies we have found that AN patients overestimate the
size of their body compared to healthy controls. After providing participants
with multisensory input as part of the Rubber Hand Illusion, AN patients*
overestimation of body size decreased (i.e. was more accurate). It appears that
multisensory stimulation contributes to changed (more accurate) body size
experience in AN.
In our previous study we focused on size experience of the hand only. In the
current study we aim to investigate whether multisensory input also affects
body size estimation of a more clinically relevant body part. Therefore we will
focus here on size experience of the abdomen before and after multisensory
stimulation.
Study objective
The main objective of the current study is investigating whether AN patients
and healthy controls differ in how they experience (estimate) the size of their
abdomen before and after multisensory input is provided (we will compare size
estimation errors before and after providing multisensory input between the
patient and healthy control group).
A first secondary objective of the current study is investigating whether they
way in which multisensory input is provided affects the change in body size
experience we expect to find in the AN group. Multisensory stimulation can take
place in a synchronous fashion (visual and tactile input are provided
simultaneously) or in a asynchronous fashion (visual and tactile input are not
aligned).
A second secondary objective of the curren study is investigating whether
changes in body size experience in the AN group are persistent over tie. Two
hours after multisensory stimulation took place, we will again ask participants
to estimate their body size.
Study design
Quasi-experimental
Study burden and risks
It is not expected, but theoretically possible that the participants experience
negative emotions during the study, for example due to tactile stimulation on
the abdomen (note that tactile input is provided with a soft brush). However,
the chance of experiencing negative emotions is thought to be minimal, since
before participation takes place the participants will be informed of the
procedures during the study and what will happen during the experiment. From
experience with previous (AN) studies we learned that participants understand
why certain methods are important for the study, and that explaining these
methods to the participants reduces concerns. In addition, the knowledge that
will be gained in the current study will not only increase our understanding of
body representation disturbances in AN, but will might have implication for
treatment of AN.
Heidelberglaan 1
Utrecht 3584CS
NL
Heidelberglaan 1
Utrecht 3584CS
NL
Listed location countries
Age
Inclusion criteria
Patients: Female, between 18 and 35 years of age, diagnosed with Anorexia Nervosa, physically non-disabled (i.e. able to perform the tasks during the experiment)
Healthy controls: Female, between 18 and 35 years of age, BMI between 18.5 and 25, no current severe mental health problems, physically non-disables (i.e. able to perform tasks during the experiment).
Exclusion criteria
Patients: Use of medication that may influence task performance due to sedative effects, drowsiness or (psycho)motor impairments, comorbid Borderline personality disorder or contact disorder, pregnancy.
Healthy controls: Use of medication that may influence task performance due to sedative effects, drownsiness, or (psycho)motor impairments, pregnancy.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL49656.041.14 |