The aim of this study is to explore whether subjectively experienced SB can be objectively assessed using computerized vision based analysis of motor performance upon awakening. Secondarily, patient experiences and data quality of the assessment…
ID
Source
Brief title
Condition
- Movement disorders (incl parkinsonism)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Spatiotemporal and kinematic data (such as walking speed, joint angles, step
length, arm swing etc) will be automatically extracted from the video
registration. Parameters extracted have been shown to be related to PD
diagnosis and disease progression. However, on forehand we do not know what
parameters will give the best indication of motor function at awakeningand we
will therefore apply a hypothesis-free approach.
Secondary outcome
Patient experiences with longitudinal camera observation and quality of the
data gathered.
Background summary
A substantial proportion of Parkinson*s disease (PD) patients experience sleep
benefit (SB); an improved mobility upon awakening, as if in the medication
induced on state. However, the relationship between the subjective experience
of SB and objective improvement in motor function is unclear. Because of
day-to-day variation in the occurrence of SB, longitudinal assessment of SB
using objective and accurate measures is highly needed
Study objective
The aim of this study is to explore whether subjectively experienced SB can be
objectively assessed using computerized vision based analysis of motor
performance upon awakening. Secondarily, patient experiences and data quality
of the assessment method will be gathered.
Study design
A cross-sectional study with a 4 week follow-up will be performed. Patients
will have a video camera, that will record from one hour before to one hour
after awakening, installed in their bedroom during the 4 week follow-up period.
Study burden and risks
This study can be classified as low risk. Patients will only be asked to
perform daily activities under normal circumstances. However, they will be
asked to perform the activity lying on a bed to standing up and walking to the
bedroom door (reference activity) a number of times in OFF medication state
during the installation of the camera. This will be guided by the research
team. The burden of this study consists of having a video camera placed in the
bedroom. To overcome privacy issues the camera will only be recording during
two hours a day (one hour before walking up until one hour after waking up).
Moreover, patients will have the possibility to turn off the camera at any
time, to erase recordings and to program to not record the next morning.
Reinier Postlaan 4
Nijmegen 6524 GC
NL
Reinier Postlaan 4
Nijmegen 6524 GC
NL
Listed location countries
Age
Inclusion criteria
-Idiopathic PD, diagnosed by a neurologist according to the UK Brain Bank criteria
-Hoehn &Yahr stage I-III
-Able to walk at least 10 meter independently.
Exclusion criteria
-PD Hoehn & Yahr stage IV-V
-Cognitive impairment (MMSE<24).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL54504.091.15 |