To test the benefit of favorite music opposite to non favorite music on pain thresholds and pain modulation in healthy volunteers.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
geen aandoeningen: gezonde vrijwilligers, pijn en pijnverwerking
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Main study parameters/endpoints: Pressure tolerance will be measured via
algometry (Wagner force, USA) on five places on the dorsal side of the non
dominant forearm and expressed in Newton (N). Electrical pain tolerance
thresholds are assessed on two places on the dorsal side of the nondominant
forearm and expressed in milliAmpere (mA). Duration in the icewaterbucket (IWB)
with the dominant hand will be recorded in seconds (s) with a maximum of three
minutes (180s). After the IWB test the pressure tolerance or the electrical
pain tolerance thresholds will be recorded again. Conditioned pain modulation
(CPM) will be calculated by use of the formula ((pressure post-pressure
pre)/pressure pre)*100 expressing the precentage of painmodulation.
Secondary outcome
Secondary endpoints are the sensitivity for pain (assessed with the Pain
Sensitivity Questionnaire (PSQ), amount and quality of sleep (Pittsburg Sleep
Quality Index) and the Quality of Life (assessed with the EQ-5D).In addition,
the subject will be asked after the completion of the investigation how
burdensome they found the measurements.
Background summary
Pain is defined as *an unpleasant sensory and emotional experience associated
with actual or potential tissue damage, or described in terms of such damage*.
The prevalence of pain in the Netherlands is around 18% (e.g. 3 million
people). There is evidence that music can be of use to reduce pain during the
postoperative period. In healthy volunteers it is shown that music reduces the
pain response. However, it is not studied if favorite music has more benefit
in tolerating pain than non-favorite music .
Study objective
To test the benefit of favorite music opposite to non favorite music on pain
thresholds and pain modulation in healthy volunteers.
Study design
Consecutive, observational study with a cross-over design.
Study burden and risks
After signing inform consent and the check of the in- and exclusion criteria
the volunteers have to fill in the three questionnaires. This will take about
15 minutes. After filing in the questionnaires the pain measurements will be
performed which will take at max 20 minutes. The whole measurement series will
take approximately 30 minutes.
In our experience, there is (almost) no risk to participate in this study.
Geert Groteplein Zuid 10
Nijmegen 6525GA
NL
Geert Groteplein Zuid 10
Nijmegen 6525GA
NL
Listed location countries
Age
Inclusion criteria
18 years or older and they have knowledge of the Dutch language.
Exclusion criteria
the use of painkillers in the last 12 hours,
use of anti-depressants,
pain in arm neck or shoulder (one or both sides),
heart problems,
neurological disorders,
psychiatric disorders,
wounds on hands or forearm,
M. Raynaud, pregnancy,
alcohol percentage of > 220 UGL.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL58775.091.16 |