The main objective of the current study is to identify task-general problem-solving processes in the brain, using model-guided and machine-learning-based analysis techniques applied to fMRI data. The secondary objectives are to identify the timing…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
geen
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The study parameters are the dynamics and topography of neural activation in
the observed fMRI data, as well as the behavioral data (reaction times,
performance) collected during the session.
Secondary outcome
n.a.
Background summary
Most of our daily activities require some form of problem solving. The key
cognitive functions that are involved - working memory, declarative memory, and
cognitive control - have been mapped onto the fronto-parietal brain network.
However, it is unclear how these crucial functions are implemented at an
algorithmic level, and how the flow of information is directed within the
network.
Study objective
The main objective of the current study is to identify task-general
problem-solving processes in the brain, using model-guided and
machine-learning-based analysis techniques applied to fMRI data. The secondary
objectives are to identify the timing and flow of information in the identified
regions and to develop a detailed algorithmic model of general problem solving
in the fronto-parietal network.
Study design
We will collect fMRI measurements while participants engage in two different
cognitive tasks. Both tasks manipulate the need for memory retrievals and the
need for the transformation of internal representations.
Intervention
n.a.
Study burden and risks
In the MRI-scanner participants will be exposed to a field-strength of 3 Tesla
and scanner noise.
Thus far there is no evidence to suggest that exposing humans to a magnetic
field of this strength has a negative influence on health. With regard to the
noise earplugs and a headphone will be provided. Subjects will not benefit
directly from participating in the study.
Nijenborgh 9
Groningen 9747 AG
NL
Nijenborgh 9
Groningen 9747 AG
NL
Listed location countries
Age
Inclusion criteria
Healthy, right-handed volunteers, aged 18-35.
Exclusion criteria
- Hearing problems.
- A history of neurological or psychiatric disorders.
- Use of drugs that might affect task performance;Due to the use of MRI scanning, several additional criteria will apply:
- MR-incompatible implants in the body (such as ear prosthesis or other metal implants).
- Any risk of having metal particles in the eyes due to manual work without proper eye protection.
- Tattoos containing red pigment.
- (Suspected) pregnancy.
- Claustrophobia.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL56755.042.16 |