Determination of the seroprevalence and occupational risk factors for zoonotic transmission of hantavirus (including SEOV) and pathogenic Leptospira in professional groups that have high-risk contact with muskrats and/or coypu and the bycatch of…
ID
Source
Brief title
Condition
- Hepatobiliary neoplasms malignant and unspecified
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Seroprevalence of hantavirus and Leptospira antibodies in muskrat/coypu
fighters , including further distinction in six different hantaviruses and
eight different Leptospira serovars ; Exposure factors associated with an
increased risk for contracting an infection caused by hantavirus and / or
Leptospira.
Secondary outcome
Seroprevalence of and exposure factors for other, possible occupational,
infections, including Lyme disease, tularemia, and hepatitis E. For this part
is no funding available yet.
Background summary
In January 2015, the presence of the Seoulvirus (SEOV) was demonstrated in
brown rats, captured in the east of the Netherlands. These brown rats have been
caught by muskrat- and coypu busters of a water board as bycatch. People who
regularly come into contact with (brown) rats or their urine / feces may have a
higher risk of becoming infected with hantavirus (including SEOV) and
leptospira.
Study objective
Determination of the seroprevalence and occupational risk factors for zoonotic
transmission of hantavirus (including SEOV) and pathogenic Leptospira in
professional groups that have high-risk contact with muskrats and/or coypu and
the bycatch of brown rats.
Study design
Observational cross-sectional study among professional groups that have
high-risk contact with muskrats and/or coypu and the bycatch of brown rats,
using serological tests and completion of a single questionnaire.
Study burden and risks
Participation consists of an (online) questionnaire and a blood sample. The
risks are negligible, as only one blood sample (finger prick) is taken, carried
out by a staff member with experience in taking blood.
Koningskade 40
Den Haag 2596 AA
NL
Koningskade 40
Den Haag 2596 AA
NL
Listed location countries
Age
Inclusion criteria
Muskrat and coypu fighters working for a district water board.
Exclusion criteria
None
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL56480.041.16 |