Our interest is to gain a better understanding about cognitive complaints, mood and fatigue in relation to cognitive deficit in adults 30 to 60 years of age after a first cardiac event.
ID
Source
Brief title
Condition
- Cardiac disorders, signs and symptoms NEC
- Cognitive and attention disorders and disturbances
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Determination Test for complex information processing (number of correct
items). Vienna Test System.
Secondary outcome
Presence of cognitive disorder as measured through these cognitive subdomains:
1) Speed of information processing:
Determination Test, Reaction Time Tests 1, 2, 3 (Vienna Test System),
Trailmakingtest A, Stroop color card and Stroop word card.
2) Executive function:
Zoo-map (BADS), Trailmakingtest B, Controlled Oral Word Association Test
(COWAT), Stroop color-word card, Trailmakingtest B.
3) Memory:
Rey Auditory Verbal Learning Test (RAVLT), digit span (WAIS II), category
fluency (GIT-2).
Presence of potential causal factors:
1) anxiety and depression: Hospital Anxiety and Depression Scale (HADS)
2) fatigue: The Fatigue Severity Scale (FSS)
3) cognitive complaints: The Cognitive Failure Questionnaire (CFQ)
Background summary
In recent studies the connection between heart disease and cognitive disorder
has become increasingly important in understanding patient complaints, symptoms
and rehabilitation to daily routines. Cognitive deficit, as well as mood
disorders and fatigue, may hinder disease management in cardiac patients.
Although this has been studied extensively in the elderly, this area is less
well researched for the group of middle-age patients. Consequently, some
cardiac patients may not be able to benefit sufficiently from cardiac
rehabilitation, as the current program requires normal cognitive function.
Middle-aged patients have many major responsibilities to return to after a
cardiac event. There is a need for a better understanding of cognitive deficits
in heart disease due to the implications of these deficits for disease
management, rate of dependence for daily activities and return to work.
Study objective
Our interest is to gain a better understanding about cognitive complaints, mood
and fatigue in relation to cognitive deficit in adults 30 to 60 years of age
after a first cardiac event.
Study design
The study proposed is cross-sectional in nature, using a matched-control
design. Quantitative data will be collected through neuropsychological tests,
self-report questionnaires and from medical files.
Study burden and risks
There are no serious health threats associated with participation in this
study.
1. Participation may lead to fatigue, as considerable attention and
concentration is required for the cognitive tasks.
2. Participation may prove to be confrontational as some tasks go well, while
others do not. Confrontation with performance may be frustrating for some
individuals.
Benefits include objective measure of cognitive functioning, fatigue,
depression and anxiety, which are reported back to participants. This extra
care and attention may contribute positively to the rehabilitation process.
Nico Bolkensteinlaan 75
Deventer 7416 SE
NL
Nico Bolkensteinlaan 75
Deventer 7416 SE
NL
Listed location countries
Age
Inclusion criteria
a) First cardiac event requiring in hospital medical intervention, 30-60 years of age.
b) Elective knee surgery, 30- 60 years of age.
Exclusion criteria
a) psychiatric disorder (history of bipolar disorder or actual psychosis)
b) current use of anti-psychotics
c) chronic pain syndrome,
d) history of contusio cerebri,
e) history of cerebral stroke
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL51448.075.15 |