Till date no (other) large long-term follow-up study of children with ACL ruptures has been published with a follow-up period of minimally 10 years. Therefor, the long-term consequences of ACL ruptures in children are still unknown, especially with…
ID
Source
Brief title
Condition
- Joint disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The aim of the present study is to evaluate the long-term consequence of ACL
ruptures in children, concerning radiological and clinical outcomes.
Primary Objective:
To evaluate the clinical outcomes concerning pain, knee function and knee
related quality of life after ten years in patients who were diagnosed with an
ACL rupture during childhood.
Secondary outcome
Secondary Objective(s):
1. To assess the presence of radiological osteoarthritis after ten years in
patients who were diagnosed with an ACL rupture during childhood.
2. To assess the activity level after ten years in in patients who were
diagnosed with an ACL rupture during childhood.
3. To assess the stability of the knee after ten years in patients in patients
who were diagnosed with an ACL rupture during childhood.
Background summary
The anterior cruciate ligament (ACL) is one of the most commonly injured
ligaments of the knee. The incidence of ACL injuries is currently estimated at
approximately 200 000 annually, with 100 000 ACL reconstructions performed each
year in the USA, and over 5000 ACL reconstructions per year in the Netherlands.
The goal of the treatment of ACL ruptures is to obtain the best functional
level for the patient without risking new injuries or degenerative changes in
the knee. There are many factors to be considered when deciding whether an ACL
rupture should be treated surgically or conservatively. Among these factors are
the degree of instability, the presence of meniscal lesions, the patient*s
level of athletic activity and the patient*s age.
At the moment there is no official registration system for ACL ruptures in
children. Therefor the exact number of children with ACL ruptures in the
Netherlands is unknown. However, the incidence of ACL ruptures in children
seems to have increased in the last two decades. This is possibly due to
increased participation in high activity sports, increased awareness or more
frequent use of imaging tools.
In adults, injury to the ACL frequently leads to posttraumatic osteoarthritis
(OA) and many surgeons had and have hope that ligament reconstruction also
would lead to a reduction of post-traumatic OA. However, the prevalence of
degenerative changes after reconstruction of the ACL ranges between 10* 87%
(Jomha, 1999)).
Current evidence shows children with instability of the knee and meniscal tears
are also at risk for developing OA. Though, a large long-term follow-up study
is not available. More long-term follow is necessary to evaluate the influence
of ACL ruptures on OA and functional outcome of the knee.
Study objective
Till date no (other) large long-term follow-up study of children with ACL
ruptures has been published with a follow-up period of minimally 10 years.
Therefor, the long-term consequences of ACL ruptures in children are still
unknown, especially with regards to OA.
The aim of our study is to evaluate the long-term radiological and clinical
outcomes of children with an ACL rupture.
Study design
The design of the study is a prospective cohort study, in which the
radiological and functional outcomes of ACL ruptures in children will be
evaluated. This is a ten-year follow-up study.
Study burden and risks
The burden is primarily time (visit of outpatient clinic, and to fill in
questionnaires). Also a limited amount of radiation is given by an x-ray of the
knee. There is no direct benefit from participation or group relatedness.
's Gravendijkwal 230
Rotterdam 3015 CE
NL
's Gravendijkwal 230
Rotterdam 3015 CE
NL
Listed location countries
Age
Inclusion criteria
A patient who visited the Sophia Children's hospital between 2000 and 2005 and were diagnosed with an anterior cruciate ligament rupture
Exclusion criteria
posterior cruciate ligament ruptures
inability to speak Dutch
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL54836.078.16 |