To determine the prevalence of posttraumatic osteoarthritis following a PLD-PLFDs in a cohort of young non-osteoporotic patients and correlation with objective and subjective outcome measures.
ID
Source
Brief title
Condition
- Fractures
- Bone and joint therapeutic procedures
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The prevalence of posttraumatic osteoarthritis.
Secondary outcome
Patient reported functional outcomes objectified with the PRWE, DASH, SF-36 and
MHQ. Objective outcomes: range of motion, grip strength.
Background summary
The development of posttraumatic osteoarthritis (PA) following perilunate
dislocations and perilunate fracture dislocations (PLD-PLFDs) has been
described. Direct and indirect joint impact loading, soft tissue injuries,
joint dislocation and intra-articular fractures, increase the risk of
progressive joint degeneration that cause PA. It is though posttraumatic
osteoarthritis develops less in younger patients. However, it might be more
invalidating for a young non-osteoporotic patient to develop posttraumatic
osteoarthritis and loss of function following PLD-PLFD than for an older
patient. The extent of the loss of function can be objectified using functional
measures, such as range of motion and grip strength. Subjective measures to
objectify loss of function as experienced by the patient can be performed using
validated questionnaires. In this study, the prevalence of posttraumatic
osteoarthritis following a PLD-PLFD in young patients is determined. Also, the
question arises what the correlation between objective and subjective outcome
measures is following a PLD-PLFD in young patients and compare these with a
healthy control group.
Study objective
To determine the prevalence of posttraumatic osteoarthritis following a
PLD-PLFDs in a cohort of young non-osteoporotic patients and correlation with
objective and subjective outcome measures.
Study design
Descriptive cohort study
Study burden and risks
none
Hanzeplein 1
Groningen 9713GZ
NL
Hanzeplein 1
Groningen 9713GZ
NL
Listed location countries
Age
Inclusion criteria
All patients treated in the period 1996 until 2014 in the University Medical Center Groningen for a PLD-PLFD - Men between the ages of 18 - 50 years and women between the ages of 18 - 40 years at the time of injury (no clinical osteoarthritis according to current available information in the literature) - Written informed consent - Mentally competent
Exclusion criteria
Preexistent osteoarthritis of the hand or preexistent declined function of the hand or wrist according to the patient - ASA III-V patients or other contra-indications for surgical treatment at the time of injury. These patients are not able to receive the most optimal treatment and thus altered outcome measures can be expected - No permanent residency (in the Netherlands) - Co-morbidity that may influence the outcomes, such as neurological of rheumatic disorders influencing arm function. - Insufficient control of the Dutch language. - No informed consent - Osteoporosis known from medical history - Pregnant women
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| Other | 22788 (voorlopig nr.) |
| CCMO | NL52111.042.15 |
| OMON | NL-OMON21645 |