To determine the sensitivity and specificity of IRT to detect clinical active arthritis in hand-joints of patients with RA or PsA using clinical examination and ultrasonography as gold standard.
ID
Source
Brief title
Condition
- Autoimmune disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main endpoint is the number of positive results of infrared-thermography
examination in hand-joints of patients with RA or PsA and clinical active
arthritis.
Secondary outcome
The secondary endpoint is the number of positive results of
infrared-thermography examination in hand-joints of patients with RA or PsA
compared to US examination.
Background summary
Arthritis is characterized by inflammation of the synovial membrane, which
could affect al joints, but small joints of the hands and feet are often
involved. Early treatment can limit the damage, therefore early recognition and
diagnosis are important. In order to prevent delay, arthritis needs to be
recognized by other specialist especially General Practitioners (GP) and
dermatologists as early as possible. At present, the standard practice for
detecting arthritis is physical examination (PE).
Useful supporting diagnostic tools for arthritis are ultrasound (US) or
Handscan. However these tools require specific expertise of a physician and
are large and not easy to apply in daily practice.
An unknown diagnostic tool for arthritis is infrared thermography (IRT). Recent
technological advances have increased the applicability. Thermal imaging
cameras are now commercially available as standalone devices and as peripheral
attachments for smartphones that provide quick assessment of environmental
thermal profiles.
The sensitivity and specificity of these cameras, to detect active arthritis in
hand-joints of patients with rheumatoid arthritis (RA) or arthritis psoriatic
(PsA), is still unknown.
Study objective
To determine the sensitivity and specificity of IRT to detect clinical active
arthritis in hand-joints of patients with RA or PsA using clinical examination
and ultrasonography as gold standard.
Study design
A mono-center, descriptive cross-sectional study.
Study burden and risks
The burden to the patient is retricted to one visit of the outpatient clinic
with the duration of an hour.
The risk is neglecteble.
's Gravendijkwal 230
Rotterdam 3015 CE
NL
's Gravendijkwal 230
Rotterdam 3015 CE
NL
Listed location countries
Age
Inclusion criteria
- 18 years or older
- Diagnosed with Arthritis Psoriatic (CASPAR criteria) or Rheumatoid Arthritis (Rheumatism classification criteria)
- Active arthritis in hand based on physical examination by a rheumatologist
Exclusion criteria
- Poor knowledge of the Dutch language
- No written informed consent
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL63716.078.17 |