To investigate the impact of (a disrupted) circadian rhythm on food preferences and chemosensory perception.
ID
Source
Brief title
Condition
- Other condition
- Appetite and general nutritional disorders
Synonym
Health condition
slaapstoornisssen
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main outcome parameters will be (changes in) food preferences and
chemosensory function.
Secondary outcome
Other study parameters will be sleep quality and duration, body temperature,
physical activity, and hunger and satiety
Background summary
Night work is a common phenomenon in 24-hour economies. In the Netherlands,
approximately 15 percent of the working population regularly works at night.
However, night work forms a mismatch with our natural rhythms of sleep, eat,
and work. This results in increased health and safety risks. Working the night
shift is associated with higher risks of coronary heart diseases, diabetes
mellitus type 2 and getting overweight. It is yet unclear what exactly causes
the increased risk of overweight in chronic night shift workers or whether this
can be solved by nutrition interventions. An altered rhythm may change dietary
patterns towards diets with more unhealthy foods. This change could be the
result of altered food preferences due to hormonal changes in hunger and
satiety. In addition, smell and taste perception have been suggested to be
influenced by diurnal rhythms. Potentially, changes in food preferences due to
an altered smell and taste perception can explain the poorer choice in dietary
intake.
Study objective
To investigate the impact of (a disrupted) circadian rhythm on food preferences
and chemosensory perception.
Study design
This observational study will be conducted in nightshift workers. Olfactory and
gustatory function and food preferences will be assessed at several time points
during a normal and a shifted circadian rhythm.
Study burden and risks
Participation in the study will not bring any risks. The only burden is the
time investment necessary for the measurements. In total it will take about 10
hours distributed over 4 days. In these 4 days, participants are asked to
complete 10 times a food preference task, a taste test, and a smell test. They
are asked to come to Wageningen University and Research 0 to 6 times.
Due to the observational design of the study, participants will not receive
short term benefits of the study. Though, at the end of the study participants
will receive the results of total smell and taste ability.
The results of the study will help us to understand and monitor changes in
chemosensory perception and food preferences and its relationship with an
altered intake frequently observed in night shift workers. We can use this
information in developing and optimizing targeted dietary guidelines for
(night) shift workers.
Stippeneng 4
Wageningen 6708WE
NL
Stippeneng 4
Wageningen 6708WE
NL
Listed location countries
Age
Inclusion criteria
Working the night shift for at least 3 months.
At least 35 years old.
Body Mass Index of at least 25 kg/m2,
Willingness to follow the study restrictions/prerequisites (not wearing perfumes and 45-120 minutes of fasting prior to each test session)
Exclusion criteria
Being pregnant in the past 6 months
Having self-reported impairments in smelling or tasting
Smoking
Have been diagnosed with narcolepsy or chronic insomnia
Having insulin dependent diabetes mellitus
Being in use of drugs that could cause or resolve sleep problems and not willing or able to stop during the 4-day study period.
Current participation in other medical research.
Reported unexplained weight loss or weight gain of > 5 kg.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL62968.081.17 |