To study the in vitro development of embryos in a pH that better resembles the pH of the uterus.
ID
Source
Brief title
Condition
- Sexual function and fertility disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Blastocyst formation rate of human preimplantation embryos in each culture
condition.
Secondary outcome
Number of cells per blastocyst and embryo gene expression patterns for each
culture condition.
Background summary
Recent research showed the pH of the uterus to be different from the pH that is
being used for the culture of embryos in the laboratory in a IVF treatment.
Study objective
To study the in vitro development of embryos in a pH that better resembles the
pH of the uterus.
Study design
Left-over embryos will be randomly allocated to two different culture
conditions.
Study burden and risks
Only left over, cryopreserved embryos are used for this study. These embryos
would be otherwise discarded. The couples that
donated these embryos have already finished their treatment. The couples have
already given written consent for the use of their left over and cryopreserved
embryos for research purposes. No additional involvement is required for the
couples therefore no burden, risk or benefit is associated with this study.
Meibergdreef 9
Amsterdam 1105 AZ
NL
Meibergdreef 9
Amsterdam 1105 AZ
NL
Listed location countries
Inclusion criteria
Left over, cryopreserved embryos that were donated with written consent from patients that underwent an IVF/ICSI treatment at the Center for Reproductive Medicine in the Academic Medical Center in Amsterdam, The Netherlands.
Exclusion criteria
NA
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL56661.000.16 |