The aim of the study is to strengthen the basis for a new application of pupillometry (i.e., the measurement of pupil dilation) within the field of Audiology. An innovative method to quantify listening effort (pupillometry) will be further developed…
ID
Source
Brief title
Condition
- Hearing disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Performance on a speech perception in noise test, pupil response.
Secondary outcome
Performance on the cognitive tasks and questionnaires.
Background summary
Hearing loss is one of the most prevalent European disabilities. It is
associated with increased levels of distress, fatigue and need for recovery.
This causes withdrawal from major social roles, such as the occupational role
and imposes a risk for the ageing European population. LISTEN aims to examine
which current and new hearing aid technologies can successfully decrease
listening effort required during speech perception.
Study objective
The aim of the study is to strengthen the basis for a new application of
pupillometry (i.e., the measurement of pupil dilation) within the field of
Audiology. An innovative method to quantify listening effort (pupillometry)
will be further developed. Novel concepts translating laboratory findings back
to daily life practice will be explored and validated.
Study design
The main study parameters in the study are:(1) The percentage of auditory
sentences perceived correctly, (2) the peak pupil dilation (PPD) in response to
the cognitive processing load during listening to speech presented in a
background of interfering speech and (3) the pupil light reflex (PLR), the
pupil response to brief exposure to light.
The PPD will be expressed relative to the pupil size during listening to
interfering speech or silence (baseline pupil size). We will assess to what
extent the speech and signal characteristics (e.g., signal levels) influence
the PPD. We will additionally assess the pupil light reflex (PLR; the
constriction of the pupil when exposed to bright light as compared to
darkness). We will also examine group effects (e.g., effects of hearing loss)
on the test performances, PPD and PLR.
Subjects additionally perform working memory and verbal inference-making tests
and complete questionnaires about daily-life (hearing) functioning and stress.
We will examine the correlation coefficients between the test performances and
speech intelligibility (percentage correct word repetition) and the pupil
parameters.
Study burden and risks
Participating with this study does not involve any health risks with careful
observation of approved safety procedures for audiological testing and
pupillometry. Pupillometry is based on recordings of a camera emitting
infra-red light at a power well below the standard safety guidelines.
Participants will perform a speech comprehension test in which they are asked
to repeat speech presented in background noise. In addition, participants will
perform several cognitive tests (reading aloud of partly masked sentences,
working memory).
Participants will spend a total of 4 hours to this study (30 minutes for those
participating in the pilot study and 60 minutes for those participating in Exp
4c).
De Boelelaan 1118
Amsterdam 1081 HV
NL
De Boelelaan 1118
Amsterdam 1081 HV
NL
Listed location countries
Age
Inclusion criteria
Age between 18 and 80 years, native Dutch speaker, normal or corrected to normal eyesight, for normally hearing listeners: age -normal hearing according to ISO 7029, 2000, for listeners with hearing loss: pure tone hearing thresholds (average across 1, 2, 4 kHz) of at least 25 dB HL in at least one ear. ;For experiment 4C: Aged 12 years up to and including 16 years, native speakers of Dutch, normal or corrected-to-normal eyesight. Listeners with hearing loss should use at least one hearing aid in daily-life. Furthermore the hearing-impaired children should have a moderately to severe binaural sensorineural hearing loss (* 35 dB HL and * 70 dB HL for both ears), and be experienced hearing aid users. Children with normal hearing should have air-conduction pure-tone thresholds of max. 20 dB HL at the octave frequencies between 500 and 4000 Hz.
Exclusion criteria
dyslexia or other reading problems, history of neurological or psychiatric diseases, eye diseases such as caused by diabetes mellitus and cataract.;Supplementary for experiment 4C: General exclusion criteria: not being able to attend regular education schools. For the hearing impaired children unilateral and conductive hearing losses are excluded.
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
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In other registers
| Register | ID |
|---|---|
| CCMO | NL49302.029.14 |