The main goal of this study is to validate the VR-game as a tool to provoke OCD symptoms and assess OCD symptom severity. The first objective is to investigate whether the VR-game is able to provoke OCD symptoms in OCD patients. The second objective…
ID
Source
Brief title
Condition
- Anxiety disorders and symptoms
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Main study parameters involve
(1) the VR-game subjective and objective output scores, in relation to
autonomic variables
(2) including heart-rate variability, skin conductance, ECG and ICG
Secondary outcome
-
Background summary
Obsessive-compulsive disorder (OCD) is a chronic debilitating psychiatric
disorder associated with significant impairment in social and occupational
functioning. Severity of OCD symptoms is currently assessed through a
clinician-rated questionnaire, the Yale-Brown Obsessive Compulsive Scale
(Y-BOCS). However, using the Y-BOCS for the assessment of OCD symptom severity
has important limitations that may under- or overestimate OCD symptom severity.
First, retrospective assessment of symptom severity is subjective to the
patient*s memory or actual state of mind. Second, the assigned Y-BOCS score is
subjective to the interpretation of the clinician.
Interestingly, virtual reality (VR) can be used to create a controlled and
standardized environment in which current symptom severity can be assessed
without the limitations of a retrospective questionnaire. VR is a relatively
new technique, starting to be implemented in the diagnostic and treatment
process of diverse mental disorders. In this research project we will
investigate a virtual reality game (VR-game) for OCD. This VR-game is
interactive and designed to provoke and assess OCD symptoms in a controlled and
standardized way. If OCD symptom severity can be assessed in this VR-game,
subjective and retrospective limitations will resolve, leading to more
accurate, efficient and objective OCD diagnostics.
Study objective
The main goal of this study is to validate the VR-game as a tool to provoke OCD
symptoms and assess OCD symptom severity.
The first objective is to investigate whether the VR-game is able to provoke
OCD symptoms in OCD patients.
The second objective is to investigate whether the VR-game is able to assess
OCD symptom severity.
Study design
This study will be performed in two groups of participants. The groups consist
of OCD patients and healthy controls.
Both groups will participate in a cross sectional study where VR-game output
scores are studied in relation to the autonomic effects.
Study burden and risks
The risk associated with participation can be considered negligible and the
burden can be considered minimal. Total participation time is 2 hours.
Meibergdreef 5
Amsterdam 1105 AZ
NL
Meibergdreef 5
Amsterdam 1105 AZ
NL
Listed location countries
Age
Inclusion criteria
Diagnosis of primary OCD by DSM-IV criteria
Age between 18-65
Exclusion criteria
Severe neurological disorders and cardiovascular disorders.
Severe comorbid axis I disorders
Alcohol or substance abuse during the last 6 months
Use of alcohol or benzodiazepines in the 24 hours prior to investigation or recreational drugs in the 72 hours prior to investigation
Abnormal hearing and uncorrected vision
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL46697.018.13 |
| OMON | NL-OMON24956 |