First objective: gain insight in the coordination of trunk, head and arm during functional tasks in healthy children and compare this with the coordination in children with DMD, SMA and CP. Second objective: investigate if newly developed supportive…
ID
Source
Brief title
Condition
- Muscle disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary study parameters will be the active range of trunk and head motion
(e.g. motion in one direction), dynamic range of trunk and head motion (e.g.
during functional arm tasks), maximal sEMG amplitude during movements as
percentage of EMG amplitude in maximal voluntary contraction (MVC) and a trunk
impairment classification score.
Secondary outcome
Secondary study parameters will be the force and/or pressure profiles as
parameters for balance and stability of the trunk, and for determination of the
kinetics.
Background summary
Children with neuromuscular diseases suffer from muscle weakness, which results
in activity limitations. The coordination between arm, trunk and head movements
is very important in performing activities of daily life (ADL) from a
wheelchair. Weakening of the muscles causes limitations in performing
activities independently, resulting in a decrease in autonomy and quality of
life.
While the coordination of arm, trunk and head movements is key in performing
functional tasks, the focus in literature and in the development of supportive
devices, is mainly on one of the three body parts. Current arm supportive
devices improve the activity level of the patients, but they cannot function
optimally because of the lack of trunk and head support.
A trunk and head supportive device will be developed, which also can interact
with the arm supportive device, in collaboration with several technical
universities. Therefore more insight is needed in the coordination between
trunk, head and arm movements in healthy children and children who suffer from
muscular weakness (i.e. Duchenne Muscular Dystrophy (DMD), Spinal Muscular
Atrophy (SMA) and Cerebral Palsy (CP)).
Study objective
First objective: gain insight in the coordination of trunk, head and arm during
functional tasks in healthy children and compare this with the coordination in
children with DMD, SMA and CP. Second objective: investigate if newly developed
supportive devices/prototypes are able to support the trunk and head
effectively during arm movements.
Study design
Explorative, cross-sectional study
Study burden and risks
The burden and risk associated with participation is limited, since the
measurements are non-invasive and the intensity is relatively low. The measured
movements are movements also performed during activities of daily living and
will not be forced.
Reinier Postlaan 2
Nijmegen 6525 GC
NL
Reinier Postlaan 2
Nijmegen 6525 GC
NL
Listed location countries
Age
Inclusion criteria
- Between age of 6 and 20 years
- Able to show arm motor skills at request
- For patient groups: genetically confirmed diagnosis of Duchenne muscular dystrophy or clinically confirmed diagnosis of cerebral palsy
Exclusion criteria
- Other disabling diseases affecting the trunk, head or arms
- Surgical scoliosis correction
- Participating in other studies at the same time
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL53143.091.15 |