To demonstrate whether a statistically significant difference exists between T2D patients with and without DR.
ID
Source
Brief title
Condition
- Retina, choroid and vitreous haemorrhages and vascular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Lp(a) concentration.
Secondary outcome
Molecular characteristics Lp(a).
Background summary
Diabetic retinopathy (DR), a microvascular complication of type 2 diabetes
(T2D), may lead to local ischemia and inflammatory reactions and, ulimately, to
irreversible vision loss. A high Lp(a) concentration comprises a risk factor
for developing cardiovascular disorders in general and, apparently also, for
DR. It is conjectured that T2D patients with DR have an increased Lp(a)
concentration (associated with a reduced number of Kringle IV repeats).
Study objective
To demonstrate whether a statistically significant difference exists between
T2D patients with and without DR.
Study design
Comparative, non-randomised, observational.
Study burden and risks
Participants do not benefit, risks are negligible, burden is low.
Schiedamse Vest 180
Rotterdam 3011 BH
NL
Schiedamse Vest 180
Rotterdam 3011 BH
NL
Listed location countries
Age
Inclusion criteria
Age >= 18 years
Informed consent
Diabetic retinopathy
Exclusion criteria
Other retinal pathology
Glaucoma
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL66405.078.18 |